ArticleFrontiers in digital health2025
Evaluating the effect of mobile applications "My A:Care" and "Smart Coach" on adherence to lipid-lowering treatment in patients with dyslipidemia: a prospective, randomized, open-label clinical study.
Article in Frontiers in digital health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05370703 (A Prospective, Randomized, Open-label, Clinical Study to Evaluate the Effect of Mobile Applications "My A), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective, Randomized, Open-label, Clinical Study to Evaluate the Effect of Mobile Applications "My A:Care" and "Smart Coach" on the Lipid-lowering Treatment Adherence of Subjects With Dyslipidemia in Thailand
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of Mobile Health for Improving Medication Adherence in Patients With Cancer: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- Artificial intelligence-enhanced management system for secondary prevention of coronary heart disease: a randomized clinical trial.BMC medicine · 2026Trial
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Dyslipidemia, a key modifiable risk factor for cardiovascular diseases, is managed using lipid-lowering therapies. Medication adherence for dyslipidemia treatment is poor across the globe, impacting treatment effectiveness. This highlights the need for scalable strategies, such as mobile app-based behavioral interventions, to enhance adherence to lipid-lowering therapies. Objective: The study assesses the impact of "My A:Care" and "My A:Care Smart Coach" mobile interventions on adherence to dyslipidemia treatment. Methods: This proof-of-concept, open-label, single-center study randomized 150 patients with suboptimal adherence to dyslipidemia treatment into three groups (1:1:1): My A:Care, My A:Care Smart Coach (intervention), and a no-app control group. Participants were monitored over 12 weeks. The primary objective was to assess changes in medication adherence, with secondary outcomes including changes in lipid parameters and beliefs about lipid-lowering medications. The study also explored the association between adherence and app engagement. Results: At week 12, the Medication Adherence Report with Visual Analog Scale (MARS-5VA) Part 1 scores were modestly, but significantly lower in the control group compared to the intervention groups: Mean (SD); No-App: -0.3 (0.9), Smart Coach: 0.0 (0.7) [ Conclusion: This proof-of-concept study suggests that the My A:Care and Smart Coach apps may positively impact adherence to lipid-lowering therapy in patients with dyslipidemia. The positive adherence outcomes and potential benefits in lipid control indicate promising early signals that warrant further investigation in larger, confirmatory studies. Clinical Trial Registration: NCT05370703.
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