ArticleHealth science reports2025
Electroacupuncture Improves Sepsis-Induced Acute Gastrointestinal Injury: A Retrospective Propensity Score-Matched Cohort Study.
Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Adjunctive acupuncture for sepsis-associated acute gastrointestinal injury: a systematic review, meta-analysis, and exploratory Bayesian network meta-analysis.Frontiers in medicine · 2026Pooled it
- Electroacupuncture for the prevention of acute gastrointestinal injury in patients with sepsis undergoing mechanical ventilation (EAGISM): a protocol for an open-label randomized controlled trial.Frontiers in medicine · 2026Article
- Shenfu injection in sepsis-induced acute gastrointestinal injury: a narrative review of mechanisms and current evidence.Frontiers in pharmacology · 2026Review
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: There is limited research on the clinical efficacy of electroacupuncture (EA) for sepsis-induced acute gastrointestinal injury (S-AGI). This study aimed to examine the effects of EA at "Zusanli" (ST36) and "Guanyuan" (RN4) on S-AGI. Methods: We identified 255 patients with S-AGI from March 2018 to September 2021 who underwent treatment at the Department of Critical Care Medicine, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine. Among these patients, 50 received EA, and 203 did not. After performing 1:2 propensity score matching by sex, age, baseline comorbidity, infection source, laboratory results, and AGI classification, there were 100 patients in the non-EA cohort. In addition to conventional therapies, patients in the treatment group underwent 30 min of EA at ST36-RN4 twice a day for 7 days. The 28-day mortality was recorded. Results: Our study included 150 participants diagnosed with S-AGI, with an average age of 70.3 years. Kaplan-Meier survival analysis indicated an association between EA treatment and significantly lower 28-day mortality. Adjusted multivariable Cox models consistently suggested a significant reduction in the prevalence of mortality that was associated with the use of EA. After accounting for confounding factors, there was an observed 54% decrease in 28-day mortality among patients who received EA (hazard ratio [HR]: 0.46, 95% confidence interval [CI]: 0.22-0.95, Conclusion: There is an indication that EA at ST36-RN4 may be associated with protective effects for patients with S-AGI.
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