Evidence map›Paper›PMID 40692340›Full record

ArticleJournal of feline medicine and surgery2025

Presumptive intramedullary intervertebral disc extrusion in 12 cats: clinical presentation, MRI findings, treatment and outcome.

Thomas Heaselgrave, Luisa De Risio, Elisabet Domínguez, Elena Scarpante, Thomas Mignan, Emili Alcoverro, Simone Spinillo, Alexandra Ferreira, Francesca Samarani, Pablo Espinosa and 2 more

Abstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Thomas HeaselgraveNeurology/Neurosurgery Service, Willows Veterinary Centre & Referral Service, Linnaeus Veterinary Limited, Solihull, UK.ORCID 0009-0005-4953-9837
Luisa De RisioMars Veterinary Health, Linnaeus Veterinary Limited, Solihull, UK.
Elisabet DomínguezDiagnostic Imaging Service, Fundació Hospital Clínic Veterinari, Universitat Autònoma de Barcelona, Spain.
Elena ScarpanteNeurology/Neurosurgery Service, Dick White Referrals, Linnaeus Veterinary Limited, Newmarket, UK.
Thomas MignanNeurology/Neurosurgery Service, Dovecote Veterinary Hospital, Castle Donington, UK.
Emili AlcoverroNeurology/Neurosurgery Service, ChesterGates Veterinary Specialists, Chester, UK.
Simone SpinilloNeurology/Neurosurgery Service, ChesterGates Veterinary Specialists, Chester, UK.
Alexandra FerreiraNeurology/Neurosurgery Service, Veterinary Specialists Scotland, Linnaeus Veterinary Limited, Livingston, UK.
Francesca SamaraniNeurology/Neurosurgery Service, Department of Clinical Studies, University of Guelph, Ontario Veterinary College (OVC), Guelph, ON, Canada.
Pablo EspinosaDiagnostic Imaging Service, Department of Clinical Studies, University of Guelph, Ontario Veterinary College (OVC), Guelph, ON, Canada.
Giulia CagnottiNeurology/Neurosurgery Service, Department of Veterinary Sciences, University of Turin, Turin, Italy.
Lluís SánchezNeurology/Neurosurgery Service, Willows Veterinary Centre & Referral Service, Linnaeus Veterinary Limited, Solihull, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectivesThis study aimed to describe the clinical characteristics, MRI findings, treatment and outcome in cats presumptively diagnosed with intramedullary intervertebral disc extrusions.MethodsA retrospective review was conducted of medical records and MRI data from cats presumptively diagnosed with intramedullary intervertebral disc extrusions. Long-term outcome (⩾6 months) was assessed through medical records, questionnaires completed by the owners or both.ResultsA total of 12 cats met the inclusion criteria. All presented with peracute or acute clinical signs, with nine having confirmed (n = 3) or possible (n = 6) external trauma based on history, physical examination or MRI findings. Seven cats were ambulatory and five were non-ambulatory. Eight cats presented with urinary incontinence; none exhibited faecal incontinence. Neuroanatomical localisation included the T3-L3 (n = 7) and L4-S3 (n = 5) spinal cord segments. MRI showed an intramedullary intervertebral disc extrusion at the following sites: T12-T13 (n = 1), T13-L1 (n = 1), L1-L2 (n = 2), L2-L3 (n = 2), L4-L5 (n = 3) and L5-L6 (n = 3). All cats underwent treatment and were discharged after a median hospitalisation time of 4 days (range 3-14). All non-ambulatory cats with available follow-up information (4/5) regained ambulation by the time of the short-term (<6 weeks) or long-term (⩾6 months) assessment. Moreover, all cats either retained or regained urinary continence by the time of discharge, the short-term (<6 weeks) or the long-term (⩾6 months) assessment. Overall, nine cats achieved a successful outcome and were considered functional pets at the short-term (<6 weeks) and/or long-term (⩾6 months) follow-up. Two cats were lost to follow-up, and one cat had perceived persistent generalised discomfort.Conclusions and relevanceMost cats presumptively diagnosed with an intramedullary intervertebral disc extrusion showed a favourable outcome with treatment in this study. This condition should be considered in cats presenting with peracute or acute signs of T3-L3 or L4-S3 spinal cord dysfunction, especially if there is a history or indication of trauma.

Indexed as

Cat DiseasesIntervertebral Disc DisplacementAnimalsCatsFemaleMagnetic Resonance ImagingMaleRetrospective StudiesTreatment Outcomeintervertebral disc diseaseIntramedullary intervertebral disc extrusionMRInon-compressive nucleus pulposus extrusion

Identifiers

PMID40692340
PMCPMC12290249

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.