Evidence map›Paper›PMID 40692276›Full record

ArticleAnnals of botany2025

Genome-wide association analysis identifies natural allelic variants associated with leaf rolling in rice (Oryza sativa L.).

Dongryung Lee, Byeong Yong Jeong, Backki Kim, Seong-Gyu Jang, Yuting Zeng, Ah-Rim Lee, Junghyun Gong, Soon-Wook Kwon, Joohyun Lee

Abstract read
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Article in Annals of botany, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Dongryung LeeDepartment of Plant Bioscience, Pusan National University, Miryang 50463, Republic of Korea.
Byeong Yong JeongDepartment of Crop Science, Konkuk University, Seoul 05029, Republic of Korea.
Backki KimDepartment of Plant Bioscience, Pusan National University, Miryang 50463, Republic of Korea.
Seong-Gyu JangDepartment of Plant Bioscience, Pusan National University, Miryang 50463, Republic of Korea.
Yuting ZengDepartment of Plant Bioscience, Pusan National University, Miryang 50463, Republic of Korea.
Ah-Rim LeeDepartment of Plant Bioscience, Pusan National University, Miryang 50463, Republic of Korea.
Junghyun GongDepartment of Plant Bioscience, Pusan National University, Miryang 50463, Republic of Korea.
Soon-Wook KwonDepartment of Plant Bioscience, Pusan National University, Miryang 50463, Republic of Korea.
Joohyun LeeDepartment of Crop Science, Konkuk University, Seoul 05029, Republic of Korea.

Funding

Ministry of Science and ICT RS-2022-00165400Rural Development Administration RS-2022-RD010353
6 · The paper itself

Abstract

BACKGROUND AND

aimsLeaf rolling in rice affects plant architecture, light interception and photosynthetic efficiency. This study aims to identify the genetic basis of adaxial leaf rolling using a genome-wide association study (GWAS) in a diverse panel of rice accessions.

methodsA GWAS was performed using 1.5 million single nucleotide polymorphisms (SNPs) across 113 rice accessions. The analysis included population structure, linkage disequilibrium, haplotype patterns and expression correlation. To validate the identified association, an additional panel of japonica inbred lines was analyzed, supporting the link between the SNP and adaxial leaf rolling. KEY

resultsA japonica-specific quantitative trait locus, qALR1, was identified on chromosome 1. A putative causal SNP was located within a shared cis-regulatory motif (RAV1-B) upstream of two candidate genes, LOC_Os01g72370 and LOC_Os01g72380. Previous studies suggest that variation in this motif can influence gene expression, supporting the hypothesis that regulatory divergence in these genes may underlie variation in leaf rolling. Validation with an expanded panel of japonica inbred lines revealed its enrichment in breeding germplasm, indicating possible historical selection.

conclusionsThis study identifies a subspecies-specific regulatory mechanism underlying adaxial leaf rolling in rice. The putative causal SNP may affect transcription factor binding and gene regulation, ultimately influencing leaf morphology. These findings offer valuable targets for optimizing canopy architecture and enhancing photosynthetic performance through molecular breeding.

Indexed as

OryzaPlant LeavesAllelesGenome-Wide Association StudyHaplotypesLinkage DisequilibriumPolymorphism, Single NucleotideQuantitative Trait Lociadaxial leaf rollingcis-regulatory motifgenome-wide association studyOryza sativa Lquantitative trait loci

Identifiers

PMID40692276
PMCPMC12464949

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.