Evidence map›Paper›PMID 40692209›Full record

ReviewAustralian veterinary journal2025

The effect of intra-articular platelet-rich plasma injection on pain and lameness in dogs with osteoarthritis.

X L Cai, S Zaki

Abstract readReview
In one paragraph

Review in Australian veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

X L CaiSydney School of Veterinary Science, Faculty of Science, The University of Sydney, Camperdown, New South Wales, Australia.ORCID https://orcid.org/0009-0005-7606-0506
S ZakiSydney School of Veterinary Science, Faculty of Science, The University of Sydney, Camperdown, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis (OA) is a prevalent and progressive degenerative joint disease in dogs, leading to chronic pain, reduced mobility, and diminished quality of life. Conventional management strategies primarily aim to alleviate and palliate clinical signs of pain and reduced mobility. Platelet-rich plasma (PRP) is an emerging regenerative therapy that has gained interest for its potential disease modifying effects, through modulating inflammation and promoting tissue repair. This paper provides a critical appraisal of current literature on the effectiveness of intra-articular injection of PRP compared to a placebo on the clinical outcomes of lameness and pain in dogs with OA. Findings from 7 studies indicate that current evidence supporting the effectiveness of PRP in reducing pain and lameness is weak. Further research in the form of large, randomised, blinded controlled clinical trials is required to further assess the efficacy of PRP.

Indexed as

Dog DiseasesLameness, AnimalOsteoarthritisPainPlatelet-Rich PlasmaAnimalsDogsInjections, Intra-ArticularPain Managementlamenessosteoarthritispainplatelet‐rich plasmaregenerative therapy

Identifiers

PMID40692209
PMCPMC12500353

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.