Evidence map›Paper›PMID 40691724›Full record

ArticleOperative Orthopadie und Traumatologie2025

[Arthroscopic matrix-associated bone marrow stimulation of ankle joint lesions].

Sebastian Frischholz, Annette Eidmann, Markus Walther, Maximilian Rudert, Ioannis Stratos

Abstract readEnglish Abstract
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In one paragraph

Article in Operative Orthopadie und Traumatologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [Ankle arthroscopy-developments, significance and perspectives].Operative Orthopadie und Traumatologie · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sebastian FrischholzOrthopädische Klinik König-Ludwig-Haus, Lehrstuhl für Orthopädie der Universität Würzburg, Brettreichstr. 11, 97074, Würzburg, Deutschland. sebastian.frischholz@uni-wuerzburg.de.
Annette EidmannOrthopädische Klinik König-Ludwig-Haus, Lehrstuhl für Orthopädie der Universität Würzburg, Brettreichstr. 11, 97074, Würzburg, Deutschland.
Markus WaltherOrthopädische Klinik König-Ludwig-Haus, Lehrstuhl für Orthopädie der Universität Würzburg, Brettreichstr. 11, 97074, Würzburg, Deutschland.
Maximilian RudertOrthopädische Klinik König-Ludwig-Haus, Lehrstuhl für Orthopädie der Universität Würzburg, Brettreichstr. 11, 97074, Würzburg, Deutschland.
Ioannis StratosOrthopädische Klinik König-Ludwig-Haus, Lehrstuhl für Orthopädie der Universität Würzburg, Brettreichstr. 11, 97074, Würzburg, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveArthroscopic matrix-associated bone marrow stimulation enables treatment of symptomatic osteochondral lesions of the ankle joint to alleviate pain and improve function. INDICATIONS: Symptomatic osteochondral lesions caused by trauma, osteochondritis dissecans, or isolated degenerative cartilage damage. Unstable lesions with nonrefixable fragments. CONTRAINDICATIONS: Acute infections, ubiquitous advanced osteoarthritis. SURGICAL TECHNIQUE: Treatment of intra-articular pathologies and resection of hypertrophic synovia. Unstable cartilage tissue is debrided, and stable margins are created. The subchondral bone is microfractured to promote bleeding and cell migration. For deeper defects, a spongiosa graft can be performed. A tailored collagen matrix is introduced through a mini-arthrotomy and fixed with fibrin glue. POSTOPERATIVE MANAGEMENT: Partial weightbearing of 10-20 kg, depending on the procedure performed. From week 7, load-bearing is gradually increased; full weight-bearing is possible after 12 weeks. Sports activities can be resumed after 6 months.

resultsIn a retrospective analysis of 10.611 inpatient procedures in Germany from 2006-2022, the numbers for arthroscopies and arthrotomies initially increased, whereby the number of arthrotomies peaked in 2020, followed by a decline. Arthroscopic procedures increased steadily, especially from 2014 onward, indicating a preference for the minimally invasive technique.

Indexed as

Ankle InjuriesAnkle JointArthroscopyBone MarrowOsteochondritisBone MatrixCartilage, ArticularHumansRange of Motion, ArticularRecovery of FunctionRetrospective StudiesTreatment OutcomeWeight-BearingAnkle jointArthroscopyCartilage regenerationOsteochondral lesionsOsteochondritis dissecans

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.