Evidence map›Paper›PMID 40691618›Full record

ArticleHead & face medicine2025

The effect of three different apical termini on postoperative pain in teeth with irreversible pulpitis: a prospective clinical study.

Fei Zhai, Haiying Zhang, Chen Zhang, Benxiang Hou

Abstract readClinical Study
In one paragraph

Article in Head & face medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fei ZhaiDepartment of Endodontics, Beijing Stomatological Hospital, Capital Medical University, No. 9 Fanjiacun Road, Beijing, Fengtai District, 100070, China.
Haiying ZhangDepartment of Endodontics, Beijing Stomatological Hospital, Capital Medical University, No. 9 Fanjiacun Road, Beijing, Fengtai District, 100070, China.
Chen ZhangDepartment of Endodontics, Beijing Stomatological Hospital, Capital Medical University, No. 9 Fanjiacun Road, Beijing, Fengtai District, 100070, China. 1465552737@qq.com.
Benxiang HouCenter for Microscope Enhanced Dentistry, Beijing Stomatological Hospital, Capital Medical University, No. 22 Xinrong Street, Beijing, DaXing District, 100162, China. endohoubenxiang@163.com.

Funding

Beijing Municipal Science & Technology Commission Z191100006619037
6 · The paper itself

Abstract

backgroundThe apical terminus of root canal preparation plays a critical role in minimizing postoperative pain. Yet, significant debate remains regarding the optimal termination point. This prospective clinical study aimed to assess the effect of three different apical termini on postoperative pain in teeth with irreversible pulpitis.

methodsTotally, 128 patients with asymptomatic or symptomatic irreversible pulpitis were consecutively enrolled. Participants underwent root canal preparation with the apical terminus positioned either at the apical foramen (AF) or 0.5 or 1 mm short of it. Pain intensity was rated using an 11-point numerical rating scale (NRS-11) at nine time points. Data were analyzed using repeated measures analysis of variance.

resultsIn cases of irreversible pulpitis without preoperative pain (NRS = 0), the pain scores at 72 h after preparation were significantly lower in the AF-1 mm group than in the AF group (P < .05), with none of the patients in the AF-1 mm group reporting pain at this time point (P < .017). In cases of irreversible pulpitis with moderate preoperative pain (NRS = 4-7), the post-preparation pain scores at 4 h was significantly lower than the preoperative pain in all groups (P < .05). The pain scores in the AF-0.5 mm group remained lower than that in the other groups at 4 h, 24 h, 72 h, and 1 week. More patients reported decreased pain 4 h postoperatively in the AF-0.5 mm group than in other groups, with all patients in the AF-0.5 mm group reporting no pain at 1 week. In cases with mild preoperative pain (NRS = 1-3), the pain scores were significantly lower 72 h postoperatively than preoperatively (P < .05), with fewer patients reporting increased pain 24 h postoperatively in the AF-0.5 mm group than other groups.

conclusionsPositioning the root canal apical terminus 0.5 and 1.0 mm short of the AF in symptomatic and asymptomatic cases of irreversible pulpitis, respectively, was most effective in reducing the severity and duration of postoperative pain. Tailoring apical preparation depth to the pulpal condition-symptomatic or asymptomatic-can optimize patient comfort and support more personalized endodontic care.

Indexed as

Postoperative PainPulpitisRoot Canal PreparationAdultFemaleHumansMaleMiddle AgedPain MeasurementProspective StudiesTreatment OutcomeYoung AdultApical foramenApical terminusEndodontic treatment outcomesIrreversible pulpitisPain managementPostoperative painRoot canal preparation

Identifiers

PMID40691618
PMCPMC12278658

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.