ArticleInternational urology and nephrology2026
The aging-related GFR decline in Chinese healthy elderly.
Article in International urology and nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo elucidate the glomerular filtration rate (GFR) decline associated with aging in healthy Chinese elderly over 65 years old.
methodsThe analysis included 5375 individuals aged 65 and older from the Pujing Community in Shanghai, China. Individuals with diabetes, hypertension, current smoking, obesity, hyperlipidemia, proteinuria, or a history of stroke or cardiovascular disease as the unhealthy cohort were excluded from the healthy cohort. We analyzed the levels and changes of eGFR at different ages to determine the effects of aging on eGFR.
resultsThe mean eGFR for healthy subjects aged 65-69, 70-74, 75-79, 80-84, and ≥ 85 years were 89.88, 85.36, 81.89, 72.08, and 71.87, respectively. These values were significantly higher than those for unhealthy subjects of the same age: 86.71, 82.21, 77.66, 66.55, and 57.97 mL/min/1.73 m
conclusionThe eGFR in healthy subjects over 65 years old in Shanghai, China declined at a rate of 0.999 mL/min/1.73 m
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