ArticleTropical animal health and production2025
Molecular characterization, isolation and population structure analysis of goatpox virus from Haryana, India.
Article in Tropical animal health and production, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Goatpox is a highly contagious viral disease of goats caused by the goatpox virus (GTPV) of the genus Capripoxvirus, family Poxviridae. The huge economic losses in outbreaks are due to hide damage, production losses and high morbidities associated with the disease. An outbreak of goatpox was investigated in a goat flock from Hisar district of Haryana, India, in April 2022 with an overall morbidity of 21%. GTPV was first identified in pock lesions using a polymerase chain reaction (PCR) assay targeting E10R and RPO132 genes and subsequently identified by isolation in Vero cells and further confirmed by sequencing of the P32 gene of GTPV. Cytopathic effects of rounding, clumping and detachment of cells were observed in Vero cells. The PCR amplification of harvested cells amplified a 955 bp specific to the P32 gene and confirmed to be GTPV by sequencing. The phylogenetic analysis revealed nucleotide identity of more than 99% with Indian isolates, signifying a close genetic relationship. Based on the median joining network analysis of P32 gene, 33 haplotypes were identified among the GTPV population. Population structure analysis revealed high haplotype (0.991 ± 0.009) and low nucleotide (0.0041 ± 0.0004) diversities and significant negative values for the neutrality indices indicating purifying selection and rapid population expansion. The findings will help to understand the distribution and dynamics of genetic differences among the GTPV populations. Further detailed studies are warranted to delineate the molecular details of the virus for better understanding the dynamics and molecular epidemiology of pox viruses in the country.
Indexed as
Identifiers
40691378What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.