ArticleAnalytical and bioanalytical chemistry2025
Ultrasensitive electrochemical immunosensor system for the determination of CD133 biomarker.
Article in Analytical and bioanalytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Cancer stem cells (CSCs) have recently emerged as important variables affecting the development or invasiveness of solid tumors. Prominin 1 (PROM1, CD133) is a frequently used CSC biomarker in various tumors, including lung cancer, and CD133 overexpression is linked to chemoresistance, cancer recurrence, and a poor prognosis. Furthermore, CD133 has a significant impact on tumor growth and metastasis. In this work, the detection of CD133 using a single-use multi-walled carbon nanotube (MWCNT)-supported immunoplatform was achieved for the first time. The immunoplatform was designed using an anti-CD133 antibody and the CD133 protein. Differential pulse voltammetry (DPV) measurements were performed between -0.20 V and 0.8 V using a 5.0 mM [Fe(CN)
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