Evidence map›Paper›PMID 40691267›Full record

ArticleScientific reports2025

Development and validation of a risk prediction model for abdominal aortic aneurysm: a nationwide population-based cohort study.

Hyung-Jin Cho, Mi-Hyeong Kim, Kyung-Jai Ko, Kang-Woong Jun, Kyung-do Han, Jeong-Kye Hwang

Abstract readValidation Study
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Prediction model for aortic dissection, aortic aneurysm, and peripheral artery disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Hyung-Jin ChoDivision of Vascular and Transplant Surgery, Department of Surgery, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 1021, Tongil-ro, Eunpyeong-gu, Seoul, 03312, Korea.
Mi-Hyeong KimDivision of Vascular and Transplant Surgery, Department of Surgery, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 1021, Tongil-ro, Eunpyeong-gu, Seoul, 03312, Korea.
Kyung-Jai KoDepartment of Surgery, Kangdong Sacred Heart Hospital, Seoul, Korea.
Kang-Woong JunDivision of Vascular and Transplant Surgery, Department of Surgery, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Gyeonggi-do, Korea.
Kyung-do HanDepartment of Statistics and Actuarial Science, Soongsil University, Seoul, Korea.
Jeong-Kye HwangDivision of Vascular and Transplant Surgery, Department of Surgery, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 1021, Tongil-ro, Eunpyeong-gu, Seoul, 03312, Korea. jjungyong@catholic.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abdominal aortic aneurysm (AAA) is characterized by irreversible localized dilatation of the abdominal aorta. It poses a significant health risk. As AAA size tends to increase over time, there is a heightened risk of rupture, resulting in a substantially high mortality rate. Although AAA screening programs targeting specific demographics are available, there is room for improvement in terms of inclusivity and cost-effectiveness. This study aimed to develop a predictive model for AAA occurrence utilizing seven years of data from the Korean National Health Insurance Service database (NHIS). This study utilized NHIS data from 2009 to 2020. A total of 4,234,415 individuals who underwent health examinations in 2009 were identified. After applying exclusion criteria, a total of 3,937,535 individuals were selected. Of them, 70% were used for model development and 30% were used for validation. The mean follow-up duration was 10.11 ± 1.29 years, during which 2,836 cases of AAA were identified among 1,181,131 (2.4%) participants in the validation cohort. The model incorporated a set of 10 variables, encompassing age, sex, obesity, smoking, drinking, diabetes (DM), hypertension (HTN), dyslipidemia, chronic kidney disease (CKD), and cardiocerebrovascular disease (CVD). Evaluation of the model's predictive performance revealed an area under the curve (AUC) of 0.807 (95% CI: 0.80-0.81) when it was applied to the development cohort. The AUC remained high at 0.803 (95% CI: 0.79-0.81) when the model was applied to the validation cohort, indicating its effectiveness in forecasting AAA occurrence. A multivariable risk model for predicting the onset of AAA was successfully developed, showcasing an excellent performance with an AUC value of 0.807, surpassing traditional screening methods. This model has the potential to selectively identify high-risk patients from a slightly broader pool than current screening approaches. Priority should be given to proactive screening efforts targeting individuals at elevated risk for AAA, with the goal of reducing AAA-related mortality.

Indexed as

Aortic Aneurysm, AbdominalAgedCohort StudiesDatabases, FactualFemaleHumansMaleMiddle AgedRepublic of KoreaRisk AssessmentRisk FactorsAbdominalAortic aneurysmNomograms

Identifiers

PMID40691267
PMCPMC12279962

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.