ArticleScientific reports2025
Bioprospecting endophytic fungi of forest plants for bioactive metabolites with anticancer potentials.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Novel production of vinblastine by immobilized cultures of mutant strain of the endophytic Alternaria alternata.World journal of microbiology & biotechnology · 2026Article
- Untapped microbial factories for next-generation therapeutics: Endophytic fungi of medicinal plants.Microbial cell factories · 2026Review
- Secondary Metabolites from Diaporthe eres SK3, an Endophytic Fungus of Sellaginella kraussiana Sw. Collected from the Northeast Indian Hills, Exhibits Potential in Vitro Bioactivities.Current microbiology · 2026Article
- Purification and characterization of a dihydroxy Oxocyclohexyl acetate derivative from endophytic Aspergillus Candidus targeting Candida albicans lanosterol 14α-Demethylase.Scientific reports · 2026Article
- Natural pigments from the endophyte Aspergillus westerdijkiae and evaluation of their bioactivities.Microbial cell factories · 2025Article
- Enhanced myco-synthesis of selenium and zinc oxide nanoparticles and evaluating their anticancer activities and role against antibiotic resistance genes in certain bacterial strains.Microbial cell factories · 2025Article
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Authors and funding
8 authors.
Funding
Abstract
Cancer continues to be a major cause of mortality worldwide, emphasizing the critical need for innovative and more effective anticancer drugs with enhanced efficacy and minimal side effects. In response, researchers have begun investigating the largely unexplored metabolites produced by fungal endophytes for the development of novel therapeutics. In this regard, the present work aims to assess the anticancer potential of the fungal endophytes of forest plants (local forest in Wrocław, Poland), which remains yet unexamined. Fungal endophytes were isolated from their host plants, purified, grown and their extracts were separately prepared from cell-free culture media and biomass. The prepared extracts were tested for their cytotoxic potentials against human melanoma, breast adenocarcinoma, lung carcinoma, and normal cell lines using the MTT-based assay. Cultures of these isolates were exposed to several doses of
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