Evidence map›Paper›PMID 40691168›Full record

ArticleScientific reports2025

Anxiolytic effect of zinc oxide gallic acid composite nanoparticles following D-galactose administration in rats.

Noreen Samad, Arslan Khalid, Natasha Manzoor, Bakar Bin Khatab Abbasi, Umer Ejaz, Ayesha Ahmad Sumra, Tahira Saleem, Mohammad Raish, Ali Irfan, Yousef A Bin Jardan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Noreen SamadDepartment of Biochemistry, Faculty of Science, Bahauddin Zakariya University, Multan, 60800, Pakistan. noreen.samad@bzu.edu.pk.
Arslan KhalidDepartment of Biochemistry, Faculty of Science, Bahauddin Zakariya University, Multan, 60800, Pakistan.
Natasha ManzoorDepartment of Biochemistry, Faculty of Science, Bahauddin Zakariya University, Multan, 60800, Pakistan.
Bakar Bin Khatab AbbasiDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, MA, 02115, USA.
Umer EjazDepartment of Biochemistry, Faculty of Science, Bahauddin Zakariya University, Multan, 60800, Pakistan.
Ayesha Ahmad SumraDepartment of Chemistry, The Women University Multan, Multan, 60000, Pakistan.
Tahira SaleemDepartment of Chemistry, Govt. Graduate College for Women Mumtazabad, Multan, Pakistan.
Mohammad RaishDepartment of Pharmaceutics, College of Pharmacy, King Saud University, 11451, Riyadh, Saudi Arabia.
Ali IrfanDepartment of Chemistry, Government College University Faisalabad, Faisalabad, 38000, Pakistan. raialiirfan@gmail.com.
Yousef A Bin JardanDepartment of Pharmaceutics, College of Pharmacy, King Saud University, 11451, Riyadh, Saudi Arabia. ybinjardan@ksu.edu.sa.

Funding

King Saud University RSP2025R457
6 · The paper itself

Abstract

D-galactose by instigating oxidative stress, inflammation, and degenerative changes, causes neurological problems, i.e., anxiety. Zinc oxide (ZnO)-gallic acid

Indexed as

Anti-Anxiety AgentsAnxietyGalactoseGallic AcidNanoparticlesZinc OxideAnimalsAntioxidantsBehavior, AnimalHippocampusMaleOxidative StressRatsRats, WistarAnti-Anxiety AgentsAntioxidantsGalactoseGallic AcidZinc Oxide5-HT-1A receptor expression5-HT metabolismAntioxidant enzymesAnxietyD-galactoseInflammatory markersZnO-gallic acidNP

Identifiers

PMID40691168
PMCPMC12280182

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.