Evidence map›Paper›PMID 40690477›Full record

ArticlePLOS global public health2025

WHO-Point prevalence survey of antibiotic use in a Senegalese tertiary care hospital.

Moustapha Diop, Fatimata Wone, Oumar Bassoum, Mariéme Ndiaye, Adji Marème Diagne, Tracie Youbong, Sokhna Moumi Mbacké Daffé, Maguette Ndoye, Ajuamendem Ghogomu Tamouh, Mamadou Wagué Gueye and 4 more

Abstract read
In one paragraph

Article in PLOS global public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Oral and plasma microbiome in the context of acute febrile illness.medRxiv : the preprint server for health sciences · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Moustapha DiopDepartment of Infectious and Tropical Diseases, Dakar Principal Hospital, Dakar, Senegal.ORCID https://orcid.org/0000-0003-4957-2264
Fatimata WoneDepartment of Infectious and Tropical Diseases, Dalal JAMM Hospital, Dakar, Senegal.
Oumar BassoumInstitute of Health and Development, Cheikh Anta Diop University of Dakar, Dakar, Senegal.ORCID https://orcid.org/0000-0001-8588-5191
Mariéme NdiayeUniversity of Health Sciences of Dakar, Dakar, Senegal.
Adji Marème DiagneUniversity of Health Sciences of Dakar, Dakar, Senegal.ORCID https://orcid.org/0009-0002-7805-4538
Tracie YoubongDepartment of Infectious and Tropical Diseases, Dakar Principal Hospital, Dakar, Senegal.
Sokhna Moumi Mbacké DafféFederation of Laboratories, Dakar Principal Hospital, Dakar, Senegal.
Maguette NdoyeFederation of Laboratories, Dakar Principal Hospital, Dakar, Senegal.
Ajuamendem Ghogomu TamouhDepartment of Human Resources, Ministry of Public Health, Yaounde, Cameroon.
Mamadou Wagué GueyeFederation of Laboratories, Dakar Principal Hospital, Dakar, Senegal.
Mor NgomFederation of Laboratories, Dakar Principal Hospital, Dakar, Senegal.
Bécaye FallLaboratory Directorate, Ministry of Health and Social Action, Dakar, Senegal.
Papa Samba BaDepartment of Infectious and Tropical Diseases, Dakar Principal Hospital, Dakar, Senegal.
Adama FayeInstitute of Health and Development, Cheikh Anta Diop University of Dakar, Dakar, Senegal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The inappropriate use of antibiotics in human medicine is one of the primary causes of antimicrobial resistance. The objective of this study was to estimate the prevalence of antibiotic use at Dakar Principal Hospital and to identify factors associated with the prescription of broad-spectrum antibiotics. This cross-sectional study, conducted according to the WHO-point prevalence survey method, included all patients hospitalized in acute care wards who presented at 8:00 AM on the day of the survey. Data were collected from 9 to 29 December 2024 on working days. Multivariate logistic regression was performed to identify factors associated with the prescription of broad-spectrum antibiotics. A total of 222 patients, predominantly male (sex ratio = 1.26), were included. The median age of patients over 2 years was 45 years (interquartile range: 29-64 years). In total, 158 antibiotic prescriptions were reported for 101 included patients, resulting in a prevalence of 45.5% (101/222) and a prescription ratio of 1.56 antibiotics per patient. The most commonly prescribed antibiotics were amoxicillin-clavulanic acid (n = 36; 16.2%), followed by ceftriaxone (n = 21; 9.5%). Community acquired infection was the most common reason for prescription (n = 86; 54.4%), and 98 prescriptions (62%) were in compliance with the local guidelines. Antibiotics from the watch group of the AWaRe classification were used in 55 patients (54.4%). According to the multivariate analysis, the presence of a healthcare-associated infection was associated with this use (OR = 12.1; 95% CI [2.62-93.7]). These antibiotics from the watch group were significantly less commonly prescribed for surgical prophylaxis (OR = 0.13; 95% CI [0.02 - 0.63]). The prevalence of antibiotic use was high in the studied facility, with more prescriptions belonging to the watch group. These results underscore the need to strengthen antimicrobial stewardship policies.

Identifiers

PMID40690477
PMCPMC12279132

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.