Evidence map›Paper›PMID 40690376›Full record

ArticleeLife2025

Neural circuit mechanisms for steering control in walking

Aleksandr Rayshubskiy, Stephen L Holtz, Alexander S Bates, Quinn X Vanderbeck, Laia Serratosa Capdevila, Victoria Rockwell, Rachel Wilson

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Article
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  14. Inhibitory control explains locomotor statistics in walkingProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Article
  16. Inhibitory control of locomotor statistics in walkingbioRxiv : the preprint server for biology · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Comparative connectomics of the descending and ascending neurons of thebioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aleksandr RayshubskiyDepartment of Neurobiology, Harvard Medical School, Boston, United States.ORCID https://orcid.org/0009-0009-3139-7606
Stephen L HoltzDepartment of Neurobiology, Harvard Medical School, Boston, United States.
Alexander S BatesDepartment of Neurobiology, Harvard Medical School, Boston, United States.
Quinn X VanderbeckDepartment of Neurobiology, Harvard Medical School, Boston, United States.
Laia Serratosa CapdevilaAelysia LTD, Bristol, United Kingdom.
Victoria RockwellDepartment of Neurobiology, Harvard Medical School, Boston, United States.
Rachel WilsonDepartment of Neurobiology, Harvard Medical School, Boston, United States.ORCID https://orcid.org/0000-0001-8573-9266

Funding

Project 4: Neural Basis of Behavioral SequencesU19NS104655 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI CLANDININ, THOMAS ROBERT · 2017 to 2021
$14.6M
Dissemination of FlyWire, A Whole-Brain Connectomics ResourceU24NS126935 · NINDS · PRINCETON UNIVERSITY · PI Mala Murthy · 2022 to 2026
$5.6M
Synaptic and Circuit Mechanisms of Olfactory ProcessingR01DC008174 · NIDCD · HARVARD MEDICAL SCHOOL · PI WILSON, RACHEL · 2006 to 2021
$5.5M
Crowdsourcing the Fly ConnectomeRF1MH117815 · NIMH · PRINCETON UNIVERSITY · PI MURTHY, MALA, SEUNG, HYUNJUNE SEBASTIAN · 2018 to 2018
$3.3M
Automating whole brain connectomics: development, validation, and application of an open toolkitRF1MH120679 · NIMH · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI BOCK, DAVI · 2019 to 2019
$1.9M
Mechanosensory feature extraction for directed motor controlR01NS101157 · NINDS · HARVARD MEDICAL SCHOOL · PI WILSON, RACHEL · 2017 to 2021
$1.8M
Dissecting sensory to motor transformations in Drosophila melanogasterF31DC015701 · NIDCD · HARVARD MEDICAL SCHOOL · PI RAYSHUBSKIY, ALEKSANDR · 2017 to 2019
$95k
Stimulus Selectivity in Drosophila Primary Mechanosensory NeuronsF31NS106982 · NINDS · HARVARD MEDICAL SCHOOL · PI HOLTZ, STEPHEN LAWRENCE · 2018 to 2019
$55k
NIDCD NIH HHS F31 DC015701NIDCD NIH HHS R01 DC008174NIDCD NIH HHS R01DC008174NIMH NIH HHS RF1 MH117815NIMH NIH HHS RF1 MH120679NINDS NIH HHS F31DC015701NINDS NIH HHS F31 NS106982NINDS NIH HHS F31NS106982NINDS NIH HHS R01 NS101157NINDS NIH HHS R01NS101157NINDS NIH HHS U19 NS104655NINDS NIH HHS U19NS104655NINDS NIH HHS U24 NS126935
6 · The paper itself

Abstract

Orienting behaviors provide a continuous stream of information about an organism's sensory experiences and plans. Thus, to study the links between sensation and action, it is useful to identify the neurons in the brain that control orienting behaviors. Here, we describe descending neurons in the

Indexed as

BrainDrosophilaDrosophila melanogasterNeural PathwaysNeuronsOrientationWalkingAnimalsdescending neuronsD. melanogastermotor controlnavigationneuroscienceolfaction

Identifiers

PMID40690376
PMCPMC12279373

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.