Evidence map›Paper›PMID 40690177›Full record

ArticlePhysical and engineering sciences in medicine2025

Advantages of carbon fibre-reinforced polyetheretherketone over titanium implants in spine SBRT: a phantom evaluation.

Simon K Goodall, Katherine Tonkin, Peter Rampant, Pejman Rowshan Farzad, Martin Ebert

Abstract read
In one paragraph

Article in Physical and engineering sciences in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Simon K GoodallSchool of Physics, Mathematics, and Computing, Faculty of Engineering and Mathematical Sciences, University of Western Australia, Crawley, WA, 6009, Australia. Simon.goodall@research.uwa.edu.au.ORCID http://orcid.org/0000-0003-3318-9703
Katherine TonkinGenesisCare, 24 Salvado Road, Wembley, WA, 6014, Australia.ORCID http://orcid.org/0000-0003-2073-3044
Peter RampantGenesisCare, 24 Salvado Road, Wembley, WA, 6014, Australia.
Pejman Rowshan FarzadSchool of Physics, Mathematics, and Computing, Faculty of Engineering and Mathematical Sciences, University of Western Australia, Crawley, WA, 6009, Australia.ORCID http://orcid.org/0000-0001-8306-7742
Martin EbertSchool of Physics, Mathematics, and Computing, Faculty of Engineering and Mathematical Sciences, University of Western Australia, Crawley, WA, 6009, Australia.ORCID http://orcid.org/0000-0002-6875-0719

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluates the clinical feasibility of spine stereotactic body radiotherapy (SBRT) in the presence of titanium and carbon fibre-reinforced polyetheretherketone (CFR-PEEK) spinal implants using custom 3D-printed phantoms. The investigation focuses on the dosimetric accuracy, imaging challenges, and achievable localisation precision. Customised 3D-printed phantoms incorporating titanium and CFR-PEEK implants were computed tomography (CT) scanned, with and without metal artefact reduction (MAR) algorithms. Localisation accuracy was tested using Elekta XVI CBCT and Brainlab ExacTrac Dynamic. The dosimetric accuracy of the Monaco treatment planning system (TPS) was assessed under simple geometric conditions and for clinically realistic VMAT plans. Patient-specific quality assurance and phantom-based measurements using ionization chambers and radiochromic film were performed to evaluate delivered dose accuracy. Both Image Guided Radiotherapy (IGRT) systems achieved sub-millimetre localisation accuracy, with maximum deviations of 0.3 mm observed for titanium implants. The Monaco treatment planning system (TPS) demonstrated accurate dose modelling, with deviations < 1% for CFR-PEEK and < 2% for titanium implants in simple homogeneous arrangements. In complex VMAT plan deliveries, dosimetric measurements showed stronger agreement with TPS predictions for CFR-PEEK implants, with deviations < 3%. Titanium-based plans exhibited greater deviations, with localised dose discrepancies exceeding clinical tolerances of 5%. The application of MAR algorithms reduced these discrepancies to < 5%, ensuring clinically acceptable dosimetric accuracy. CFR-PEEK implants enhance clinical workflows due to reduced imaging artefacts and smoother dose distributions, making MAR corrections unnecessary. For titanium implants, MAR is essential to achieve clinically acceptable dosimetric accuracy, highlighting the robustness of CFR-PEEK for spine SBRT.

Indexed as

CarbonCarbon FiberKetonesPhantoms, ImagingPolyethylene GlycolsProstheses and ImplantsRadiosurgerySpineTitaniumBenzophenonesHumansPolymersPrinting, Three-DimensionalRadiotherapy DosageRadiotherapy Planning, Computer-AssistedBenzophenonesCarbonCarbon FiberKetonespolyetheretherketonePolyethylene GlycolsPolymersTitanium3D-printed phantomsCFR-PEEK implantsMetal artefact reduction (MAR)Spine SBRTTitanium implants

Identifiers

PMID40690177
PMCPMC12511253

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.