Evidence map›Paper›PMID 40690175›Full record

Observational studyObesity surgery2025

Predictors of Low Muscle Strength and Reduction in Fat-Free Mass in Multi-Ethnic Asian Populations Undergoing Bariatric-Metabolic Surgery.

Bryant Low, Marco Lizwan, Sarah Tan, Cindy Ng, Irene Chu, Zhen Jin Lee, Alvin Eng, Eugene Lim, Weng Hoong Chan, Jeremy Tan and 7 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Bryant LowSingapore General Hospital, Singapore, Singapore. bryant.lowzx@gmail.com.
Marco LizwanSingapore General Hospital, Singapore, Singapore.
Sarah TanSingapore General Hospital, Singapore, Singapore.
Cindy NgSingapore General Hospital, Singapore, Singapore.
Irene ChuSingapore General Hospital, Singapore, Singapore.
Zhen Jin LeeSingapore General Hospital, Singapore, Singapore.
Alvin EngSingapore General Hospital, Singapore, Singapore.
Eugene LimSingapore General Hospital, Singapore, Singapore.
Weng Hoong ChanSingapore General Hospital, Singapore, Singapore.
Jeremy TanSingapore General Hospital, Singapore, Singapore.
Hong Chang TanSingapore General Hospital, Singapore, Singapore.
Emily HoSingapore General Hospital, Singapore, Singapore.
Jean-Paul KovalikDuke-NUS Medical School, Singapore, Singapore.
Orlanda GohSingapore General Hospital, Singapore, Singapore.
Jacqueline SimSingapore General Hospital, Singapore, Singapore.
Phong Ching LeeSingapore General Hospital, Singapore, Singapore.
Chin Hong LimSingapore General Hospital, Singapore, Singapore. lim.chin.hong@singhealth.com.sg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBariatric-metabolic surgery (BMS) reduces muscle mass due to rapid weight loss. The objective is to assess the prevalence of pre-operative low muscle strength and predictors of post-operative low muscle strength in Asian populations undergoing BMS.

methodsThis observational study included BMS patients from a single centre between January 2022 and May 2024. Baseline demographics, anthropometric data and pre-operative muscle strength (via handgrip strength, 30-s and 1-min sit-to-stand-test) were collected. Low muscle strength was diagnosed using age-, sex- and ethnicity-specific cutoffs. Post-operative outcomes included hospital stay duration, 30-day adverse events, weight loss and strength at 6 months.

resultsThree hundred twenty-four participants were included (96 male, mean age 39.2 years, mean pre-op BMI 42.3), with low muscle strength observed in 162 (50%). This group had a higher pre-operative BMI compared to the normal muscle strength group (43.5 vs 41.0, p = 0.002). Indian participants had the highest prevalence of low muscle strength (p = 0.043). There were no significant differences in age, sex and biochemical markers between the groups. Post-operatively, there were no significant differences in complications and length of stay between the groups. At 6 months, 60.4% maintained muscle strength, while 14.2% showed a ≥ 10% decline. Adjusting for age, gender, pre-operative BMI and surgery type, higher pre-operative BMI was significantly associated with muscle strength drop of ≥ 10%.

conclusionsLow muscle strength was prevalent in 50% of Asian BMS candidates, with higher BMI and Indian ethnicity identified as potential associated factors. In a subset with follow-up data, higher BMI predicted strength loss ≥ 10% post-operatively. Further longitudinal studies with validated strength measures are needed to confirm these associations.

Indexed as

Bariatric SurgeryMuscle StrengthObesity, MorbidAdultAsian PeopleBody Mass IndexFemaleHand StrengthHumansMaleMiddle AgedPostoperative ComplicationsPrevalenceWeight LossAsian populationBariatric-metabolic surgeryMuscle strengthObesityPrevalenceSarcopenia

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.