Evidence map›Paper›PMID 40690120›Full record

ReviewAnnals of biomedical engineering2025

Advancing Bioprinting Technology Utilizing Portable Bioprinters: From Various Device Designs to Dental Applications.

YongJu Chen, MengJie Kong, Tingting Zhang, JiaXin Li

Abstract readReview
PubMed Publisher
In one paragraph

Review in Annals of biomedical engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

YongJu Chen *School of Stomatology, Stomatological Hospital, Southern Medical University, No.366 Jiangnan Dadao Nan, Haizhu District, Guangzhou, 510220, Guangdong, China.
MengJie Kong *Paediatric Dentistry and Orthodontics, Faculty of Dentistry, Prince Philip Dental Hospital, The University of Hong Kong, 34 Hospital Road, Sai Ying Pun, Hong Kong.
Tingting ZhangSchool of Stomatology, Stomatological Hospital, Southern Medical University, No.366 Jiangnan Dadao Nan, Haizhu District, Guangzhou, 510220, Guangdong, China.
JiaXin LiSchool of Stomatology, Stomatological Hospital, Southern Medical University, No.366 Jiangnan Dadao Nan, Haizhu District, Guangzhou, 510220, Guangdong, China. lijx96@mail3.sysu.edu.cn.

Funding

Medical Science and Technology Foundation of Guangdong Province A2024339Medical Science and Technology Foundation of Guangdong Province A2024497
6 · The paper itself

Abstract

Recent advancements in portable bioprinting technology present transformative opportunities for dental applications, enabling handy fabrication of biologically functional tissues. This narrative review examines the current state of portable bioprinting systems, focusing on their potential to address critical challenges in restorative dentistry, periodontal regeneration, and endodontic therapy. We summarize key innovations in handheld bioprinting devices, emphasizing their operational mechanisms, bioink developments, and clinical applicability. Particular attention is given to four-dimensional (4D) bioprinting approaches that leverage stimuli-responsive materials for dynamic tissue reconstruction. While demonstrating promising results in pulp vascularization and defect repair, portable bioprinters face significant limitations in precision, scalability, and reproducibility due to their manual operation and environmental sensitivity. We evaluate these technical constraints and propose solutions through emerging technologies such as robotic-assisted printing, artificial intelligence-driven process optimization, and smart bioink formulations. The discussion extends to standardization protocols and regulatory considerations necessary for clinical translation. Looking forward, we highlight interdisciplinary strategies to bridge existing gaps between laboratory innovation and clinical implementation. By addressing current challenges in automation, material science, and quality control, portable bioprinting could revolutionize personalized dental care, offering biologically integrated solutions that surpass conventional synthetic alternatives. This narrative review provides both a comprehensive assessment of the progress in this field and a roadmap for future development toward clinically viable systems.

Indexed as

BioprintingDentistryEquipment DesignHumansPrinting, Three-Dimensional4D printingBioprintingDental pulpPortable bioprintersRegeneration

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.