Evidence map›Paper›PMID 40690008›Full record

ArticleJournal of neural transmission (Vienna, Austria : 1996)2026

Association of blood pressure variability with white matter hyperintensities and nigrostriatal dopaminergic deficits in drug-naïve Parkinson's disease.

Hiromasa Matsuno, Tadashi Umehara, Masahiro Mimori, Masakazu Ozawa, Tomotaka Shiraishi, Asako Onda, Keiko Bono, Shusaku Omoto, Renpei Sengoku, Hidetomo Murakami and 1 more

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Article in Journal of neural transmission (Vienna, Austria : 1996), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hiromasa MatsunoDepartment of Neurology, The Jikei University School of Medicine, Tokyo, Japan.
Tadashi UmeharaDepartment of Neurology, The Jikei University School of Medicine, Tokyo, Japan. tumety@jikei.ac.jp.ORCID http://orcid.org/0000-0003-4156-5617
Masahiro MimoriDepartment of Neurology, The Jikei University School of Medicine, Tokyo, Japan.
Masakazu OzawaDepartment of Neurology, The Jikei University School of Medicine, Tokyo, Japan.
Tomotaka ShiraishiDepartment of Neurology, The Jikei University School of Medicine, Tokyo, Japan.
Asako OndaDepartment of Neurology, The Jikei University School of Medicine, Tokyo, Japan.
Keiko BonoDepartment of Neurology, The Jikei University School of Medicine, Tokyo, Japan.
Shusaku OmotoDepartment of Neurology, Katsushika Medical Center, The Jikei University School of Medicine, Tokyo, Japan.
Renpei SengokuDepartment of Neurology, Daisan Hospital, The Jikei University School of Medicine, 4-11-1 Izumihoncho, Komae-Shi, Tokyo, 201-8601, Japan.
Hidetomo MurakamiDepartment of Neurology, The Jikei University School of Medicine, Tokyo, Japan.
Yasuyuki IguchiDepartment of Neurology, The Jikei University School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blood pressure variability, white matter brain lesions and degeneration of nigrostriatal dopaminergic neurons may be associated with each other in patients with Parkinson's disease (PD). We examined the coefficient of variation of systolic blood pressure (CV-sBP) in 122 drug-naïve patients with newly diagnosed PD. The association of CV-sBP with degree of white matter hyperintensities and striatal specific binding ratio (SBR) of

Indexed as

Blood PressureCorpus StriatumParkinson DiseaseSubstantia NigraWhite MatterAgedDopamineDopaminergic NeuronsFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedTomography, Emission-Computed, Single-PhotonTropanes2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropaneDopamineTropanesBlood pressure variabilityCaudateNigrostriatal dopamineParkinson’s diseaseWhite matter hyperintensities

Identifiers

PMID40690008

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.