SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026
Extent of fatty infiltration in lumbar paraspinal muscles in adults with degenerative scoliosis: segmental differences in muscle involvement.
Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparative clinical performance of robotic-assisted systems in spinal deformity surgery: focus on perioperative outcomes and pedicle screw accuracy.Journal of robotic surgery · 2026Pooled it
- Association of supine apical vertebral rotation with three-dimensional deformity and global spinal alignment in adult degenerative scoliosis: a retrospective study.Frontiers in medicine · 2026Article
- Pathogenic mechanisms of adult degenerative scoliosis.Frontiers in cell and developmental biology · 2026Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWith increased life expectancy, age-related spinal disorders such as adult degenerative scoliosis (ADS) are becoming more prevalent. However, few studies have comprehensively evaluated the role of lumbar paraspinal muscles in the pathogenesis of ADS. This study aimed to (1) systematically review current literature on the association between paraspinal muscles and ADS and (2) compare lumbar paraspinal muscle fatty infiltration between age- and sex-matched individuals with and without ADS, stratified by treatment type.
methodsFor the first part of the study, a systematic literature review was conducted using PubMed/MEDLINE databases, following PRISMA guidelines, to identify studies on the role of paraspinal muscles in ADS. For the second part, a total of 145 participants were evaluated: 40% (n = 58) were controls, 32.4% (n = 47) had conservatively managed ADS, and 27.6% (n = 40) had surgically treated ADS. Fatty infiltration of the multifidus, erector spinae, and psoas muscles was assessed via lumbar spine magnetic resonance imaging at three curve locations: apex, above the apex, and below the apex.
resultsCompared with controls, patients with ADS exhibited significantly higher fatty infiltration in the multifidus, erector spinae, and psoas muscles on the concave and convex sides of the curve. Logistic regression analysis revealed that each one-point increase in fatty infiltration score of the concave-sided multifidus and psoas at the apex was associated with a 2.3-fold and 4.1-fold increased likelihood of having ADS, respectively. Additionally, a one-point increase in fatty infiltration in the concave-sided psoas above the apex and the convex-sided psoas below the apex was associated with 6.9-fold and 2.7-fold increased odds of ADS, respectively.
conclusionFatty infiltration in the psoas muscle may contribute to the early development of ADS, while increased fatty infiltration in the concave-sided multifidus at the apex may influence surgical decision-making. Comprehensive assessment of lumbar paraspinal muscles is essential for optimizing management strategies in patients with ADS.
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Registered trials
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