Evidence map›Paper›PMID 40689980›Full record

ArticlePediatric radiology2025

Fetal and neonatal postmortem magnetic resonance imaging clinical protocol: recommendations from the European society of paediatric radiology postmortem task force.

Aurélie D'Hondt, Susan Shelmerdine, Michael Aertsen, Marie Cassart, Elka Miller, Willemijn Klein, Stacy Goergen, Teresa Victoria, Eléonore Blondiaux, Marianne Alison and 8 more

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Article in Pediatric radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Forensic neuropathology: 2026 update.Free neuropathology · 2026
    Review
  6. Toward structured fellowships in fetal neuroimaging.Acta obstetricia et gynecologica Scandinavica · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Aurélie D'HondtHospital for Sick Children, 555 University Avenue, Toronto, M5G 1X8, Canada. aurelie.dhondt@outlook.com.
Susan ShelmerdineGreat Ormond Street Hospital, London, United Kingdom.
Michael AertsenUniversitair Ziekenhuis Leuven, Leuven, Belgium.
Marie CassartHôpitaux Iris Sud, Brussels, Belgium.
Elka MillerHospital for Sick Children, 555 University Avenue, Toronto, M5G 1X8, Canada.
Willemijn KleinRadboud University Nijmegen Medical Centre, Nijmegen, Netherlands.
Stacy GoergenMonash Health, Melbourne, Australia.
Teresa VictoriaMassachusetts General Hospital, Boston, United States.
Eléonore BlondiauxHôpital Armand-Trousseau, Paris, France.
Marianne AlisonHôpital Robert-Debré, Paris, France.
Christian AbelJohn Hunter Hospital, Newcastle, Australia.
Ajay TaranathWomen's and Children's Hospital, Adelaide, Australia.
Monica Rebollo PoloUniversity Hospital of Geneva, Geneva, Switzerland.
Mariana L MeyersChildren's Hospital Colorado, Aurora, United States.
Marta Gomez-ChiariHospital Sant Joan de Déu Barcelona, Barcelona, Spain.
Padma RaoRoyal Children's Hospital, Melbourne, Australia.
Rick R van RijnAmsterdam University Medical Centers, Amsterdam, Netherlands.
Owen ArthursGreat Ormond Street Hospital, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostmortem magnetic resonance imaging (PMMRI) following fetal and perinatal demise is increasingly used in clinical practice as a non-invasive adjunct or alternative to autopsy. Imaging protocols vary widely between centers and there is currently no consensus.

objectiveFrom expert consensus, we aimed to develop two PMMRI protocols for pragmatic clinical perinatal imaging: first, a standardized "minimal" PMMRI clinical protocol (with the minimum essential sequences needed per body part), and second, an "ideal" PMMRI clinical protocol with the ideal full protocol, time allowing. MATERIALS AND

methodsA modified Delphi survey was conducted, between July and November 2024, among members of the European Society of Paediatric Radiology (ESPR) postmortem (PM) Task Force, of the PM imaging committee of the Society for Pediatric Radiology (SPR) and the Australian and New Zealand Society for Paediatric Radiology (ANZSPR). The survey was based on two pre-existing published PMMRI protocols and consisted of two multiple-choice tables which included all the MRI sequences in different planes according to each body part with an additional 10 PMMRI organizational questions (three of which were free text, seven multiple choice). An email containing the link to the survey was sent to 22 members of the different international PM imaging taskforces, recruited on a voluntary basis, given their clinical interest and experience in practicing perinatal PM imaging. The results were collected and analyzed in a descriptive manner, and a point-of-care PMMRI clinical protocol was established based on the recommendations of our expert panelists.

resultsNineteen PM imaging specialists from 17 centers worldwide (Europe, the USA, Canada, Australia, and New Zealand) completed the survey and formed our expert panel. By consensus (defined as > 60% agreement), the final "minimal" PMMRI clinical protocol includes three-dimensional (3-D) isovolumetric T2- and T1-weighted sequences of brain (72.2% and 77.8% respectively) and chest-abdomen-pelvis (83.3% and 77.8% respectively). The "ideal" PMMRI clinical protocol includes 3-D isovolumetric T2- and T1-weighted sequences of the whole body (66.7-100%; 61.1 - 91.7% respectively) with axial susceptibility-weighted imaging (SWI) (81.3%) and diffusion-weighted imaging (DWI) (68.8%) of the brain. Additional sequence if time allows is axial T2 turbo spin echo (TSE) (56.3%) of the brain.

conclusionAs a minimum, 3-D isovolumetric T1- and T2-weighted sequences of the brain and body, acquired together in a single station, should be performed as part of a perinatal clinical PMMRI protocol. We hope these recommendations will facilitate the standardization and globalization of perinatal PMMRI in clinical practice.

Indexed as

Clinical ProtocolsFetusMagnetic Resonance ImagingAdvisory CommitteesAutopsyDelphi TechniqueEuropeFemaleHumansInfant, NewbornPostmortem ImagingPregnancySocieties, MedicalConsensus recommendationsMRIPerinatal deathPostmortem imagingProtocol

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.