Evidence map›Paper›PMID 40689878›Full record

ArticleNeuropsychology2025

Joint effects of human immunodeficiency virus (HIV) and cannabis on neurocognition.

Ashley R Adams, Sarah M Lehman, Erin L Thompson, Christine M Kaiver, Diego Lopez, Samuel W Hawes, Brenda Lerner, Catalina Lopez-Quintero, Raul Gonzalez

Abstract read
In one paragraph

Article in Neuropsychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ashley R AdamsDepartment of Psychology, Florida International University.ORCID 0000-0002-5187-0159
Sarah M LehmanDepartment of Psychology, Florida International University.
Erin L ThompsonDepartment of Psychology, Florida International University.
Christine M KaiverDepartment of Psychology, Florida International University.
Diego LopezDepartment of Psychology, Florida International University.
Samuel W HawesDepartment of Psychology, Florida International University.
Brenda LernerDepartment of Epidemiology, Health Promotion and Disease Prevention, Florida International University.
Catalina Lopez-QuinteroDepartment of Epidemiology, University of Florida.
Raul GonzalezDepartment of Psychology, Florida International University.ORCID 0000-0002-5431-4828

Funding

The Impact of Cannabis Use on the Neurocognitive Functioning of Individuals withR01DA033156 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI GONZALEZ, RAUL · 2012 to 2017
$2.2M
Training Program in Adolescent Substance Use Disorders and Co-Occurring Mental and Behavioral DisordersT32DA043449 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI Raul Gonzalez · 2019 to 2026
$1.7M
National Institutes of Health; National Institute on Drug AbuseNIDA NIH HHS R01 DA033156NIDA NIH HHS T32 DA043449
6 · The paper itself

Abstract

objectiveCannabis has become increasingly accessible to populations living with chronic health conditions such as HIV. Many people living with HIV are turning to cannabis for symptom relief despite the unclear risks to neurocognitive health. Our study sought to replicate and extend prior research by examining global and domain-specific neurocognitive performance between four groups stratified by use of cannabis (CB; CB+/CB-) and HIV serostatus (HIV+/HIV-).

methodOur demographically diverse community sample (

resultsBetween-group comparisons revealed nonsignificant differences in global or domain-specific neurocognitive performance. However, the CB+/HIV+ group was three times (99% CI [1.18, 9.57]) more likely to be labeled with a memory impairment compared to the control (CB-/HIV-), and the CB+/HIV- group was twice (99% CI [.14, 7.47]) as likely to be labeled with an executive functioning impairment compared to the control. We also identified an interactive effect between the past 30-day CU and HIV serostatus for global (

conclusionsAlthough we conclude that recent and heavy CU poses risk of neurocognitive decline among people living with HIVs, this effect is modest. Physicians and patients must weigh a possible decrease in global and motor neurocognition against the severity of symptoms being treated. (PsycInfo Database Record (c) 2025 APA, all rights reserved).

Indexed as

CannabisCognitive DysfunctionHIV InfectionsAdultFemaleHumansMaleMiddle AgedNeuropsychological Tests

Identifiers

PMID40689878
PMCPMC12483287

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.