ArticleACS nano2025
Polyethylene and Polyvinyl Chloride Nanoplastics in Human Follicular Fluid and Seminal Plasma: Impact on Fertilization and Sperm Quality.
Article in ACS nano, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Micro- and nanoplastics in human biological materials: a systematic review of detection methods and methodological challenges.Archives of toxicology · 2026Pooled it
- Seminal Extracellular Vesicles as Molecular Modulators of Male Reproductive Function.Reproduction in domestic animals = Zuchthygiene · 2026Review
- Review
- Ovarian toxic effects of micro- and nanoplastics (Review).Experimental and therapeutic medicine · 2026Review
- Effects of micro- and nano-plastics exposure on cellular senescence: an overview.Archives of toxicology · 2026Review
- Emerging evidence on micro- and nanoplastics carcinogenicity: mechanisms, models, and signaling networks.Molecular cancer · 2026Review
- Glycine alleviates ovarian granulosa cell ferroptosis induced by ERα-mediated internalization of polystyrene microplastics.Communications biology · 2026Article
- Combined exposure to titanium nanoparticles and nanoplastics damages the male reproductive system and sperm activity.Materials today. Bio · 2026Article
- Microplastics in the seminal microenvironment of boar semen: associations with sperm motility and antimicrobial susceptibility.Frontiers in veterinary science · 2026Article
- Replacement bisphenols, phthalates, and micro-/nanoplastic exposures in human reproductive endocrinology.Frontiers in endocrinology · 2026Review
- Curcumin Mitigates Microplastic-Induced Damage in Livestock and Poultry: Mechanistic Insights and Strategies for Sustainable Farming.Veterinary sciences · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plastic pollution is a growing global issue, with nanoplastics (NPs) posing a greater threat than microplastics. Micro/nanoplastics have been detected in various human tissues and bodily fluids, but their impacts on human fertility remain unclear. We used pyrolysis gas chromatography-mass spectrometry (Py-GC/MS) with liquid extraction to detect NPs in the follicular fluid (FF) and seminal plasma (SP) of 51 couples undergoing in vitro fertilization (IVF) to investigate the impact of NPs on fertility. In our study, polyethylene (PE) and polyvinyl chloride (PVC) were the most frequently detected NPs. In FF, the average PE and PVC concentrations were 1.21 μg/g and 1.85 μg/g, respectively, whereas in SP, they were 3.02 μg/g and 2.67 μg/g, respectively. For NPs in FF, no significant association was detected between PE or PVC levels and the ovarian reserve, whereas IVF data indicated that higher PE concentrations in the T2 and T3 groups were associated with significantly lower fertilization rates than those in the low-concentration T1 group (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.