Evidence map›Paper›PMID 40689405›Full record

ArticleJournal of the American College of Emergency Physicians open2025

Management of Primary Spontaneous Pneumothorax in the Emergency Department: A Cost-Effectiveness Analysis.

Margaret L Davis, Jane Hall, R Andrew Taylor, Robert Klemisch, Farhood Farjah, M Kennedy Hall

Abstract read
In one paragraph

Article in Journal of the American College of Emergency Physicians open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Margaret L DavisDepartment of Emergency Medicine, University of Washington, Seattle, Washington, USA.
Jane HallDepartment of Emergency Medicine, University of Washington, Seattle, Washington, USA.
R Andrew TaylorDepartment of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Robert KlemischDepartment of Emergency Medicine, University of Washington, Seattle, Washington, USA.
Farhood FarjahDepartment of Surgery, University of Washington, Seattle, Washington, USA.
M Kennedy HallDepartment of Emergency Medicine, University of Washington, Seattle, Washington, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Primary spontaneous pneumothorax (PSP) is a common emergency condition among healthy individuals that presents significant management challenges, particularly in cases of moderate-to-large collapse, which have traditionally required intervention. Recent trials, including a landmark-randomized trial, have demonstrated effectiveness in 4 separate strategies: (1) observation only, (2) needle aspiration, (3) small-bore chest tubes with a 1-way valve, and (4) small-bore chest tubes with continuous suction. We compare the cost-effectiveness of these 4 strategies. Methods: We conducted a cost-effectiveness analysis from a US healthcare system perspective to compare 4 management strategies for moderate-to-large PSP in stable adult emergency department patients. Using published randomized controlled trials and secondary data, we developed a decision-analytic model with a lifetime horizon. Costs (2022 USD), quality-adjusted life-years, and net monetary benefit (NMB) were calculated at a $50,000/quality-adjusted life-years willingness-to-pay threshold and 3% annual discount. We performed 1-way and probabilistic sensitivity analyses to test the robustness of findings. Results: Base case analysis identified observation only as the most cost-effective strategy, achieving the highest NMB ($43,696). The NMB values for small-bore chest tubes with a 1-way valve, needle aspiration, and small-bore chest tube with continuous suction were $33,520, $29,465, and $12,831, respectively. Sensitivity analyses indicated that factors such as initial success rates for observation and needle aspiration influenced model outcomes, whereas probabilistic simulations confirmed observation only as the dominant strategy. Conclusions: Observation alone is the most cost-effective initial strategy for stable moderate-to-large PSP, although its feasibility may be limited. Among interventional options, a small-bore chest tube with a 1-way valve offers the best value and enables outpatient management. Further studies in diverse settings are needed to confirm the practicality of observation only care and consider individual patient factors.

Indexed as

cost-effectiveness analysisdecision-analytic modelinghealth economicsneedle aspirationnet monetary benefitobservationprimary spontaneous pneumothoraxprobabilistic sensitivity analysissmall-bore chest tube

Identifiers

PMID40689405
PMCPMC12271783

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.