Evidence map›Paper›PMID 40689377›Full record

ArticleRegenerative therapy2025

Fabrication of Piezo1 protein encapsulated pressure-sensitive multifunctional hydrogel in modulating cellular response and wound healing in pressure ulcer conditions.

Jing Ning, Feng Li, Zhi Xin Pei, Zhi Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Regenerative therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jing NingDepartment of Medical Cosmetic, Burn and Plastic Surgery, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, 030032, China.
Feng LiDepartment of Medical Cosmetic, Burn and Plastic Surgery, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, 030032, China.
Zhi Xin PeiDepartment of Medical Cosmetic, Burn and Plastic Surgery, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, 030032, China.
Zhi LiDepartment of Medical Cosmetic, Burn and Plastic Surgery, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, 030032, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pressure ulcers (PUs) are prevalent skin lesions characterized by significant morbidity, susceptibility to infection, and a complex healing process. This study aims at the synthesis of piezo1 protein-encapsulated, pressure-sensitive multifunctional hydrogel to modulate cellular response and promote wound healing in PUW conditions. The hydrogel synthesized from carboxyl methyl cellulose hydrogel exhibits the optimal swelling ratio and is found to have a high storage modulus (G'). This shows the mechanical strength and viscoelastic nature of the synthesized hydrogel. The PP encapsulation and releasing efficiency has been analyzed, and this proves the prolonged activation of mechanotransduction properties.

Indexed as

Multifunctional hydrogelPiezo1 proteinPressure ulcerWound healing

Identifiers

PMID40689377
PMCPMC12274771

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.