ArticleFrontiers in neurology2025
Gender differences in prescribing patterns for patients with Parkinson's disease in Japan: a retrospective observational study using insurance claims databases.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Parkinson's disease (PD) is a neurodegenerative disorder, with increasing prevalence among aging populations. Gender differences in PD extend to symptom presentation and treatment response, suggesting the need for gender-specific management strategies. Methods: This gender-stratified analysis of a retrospective observational study used data from three nationwide Japanese healthcare databases. Patients aged ≥30 years diagnosed with PD between June 2016 and May 2021 were included. Patient demographics, prescribing patterns, and levodopa dosages were analyzed descriptively. Results: Of 39,731 patients with PD identified, females ( Conclusion: This analysis highlights the high number of elderly female patients with PD in Japan. Slight gender differences in maximum levodopa dose and prescriptions for anti-PD drugs were observed. These findings emphasize the importance of personalized treatment approaches in PD management considering gender-specific differences in drug efficacy and side effects. Clinical trials registration: https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000053425, identifier UMIN000046823.
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