Evidence map›Paper›PMID 40689314›Full record

ArticleAmerican journal of clinical and experimental immunology2025

Impact of lactobacillus probiotics on vaccine response in diabetic rats: modulation of inflammatory cytokines.

Jehan Alrahimi, Asmaa Alrobai, Alawiah Alhebshi, Hadel M Alghabban, Sahar El Hadad

Abstract read
In one paragraph

Article in American journal of clinical and experimental immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jehan AlrahimiDepartment of Biological Sciences, Faculty of Science, King Abdulaziz University Jeddah 21859, Saudi Arabia.
Asmaa AlrobaiDepartment of Biological Sciences, Faculty of Science, King Abdulaziz University Jeddah 21859, Saudi Arabia.
Alawiah AlhebshiDepartment of Biological Sciences, Faculty of Science, King Abdulaziz University Jeddah 21859, Saudi Arabia.
Hadel M AlghabbanDepartment of Basic Medical Science, College of Medicine, Taibah University Madinah 42353, Saudi Arabia.
Sahar El HadadDepartment of Biological Sciences, Faculty of Science, King Abdulaziz University Jeddah 21859, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymph nodes are essential for immune function as they contain immune cells that activate responses and filter pathogens from lymph. This study investigates how diabetes-related metabolic challenges affect immune function, focusing on the impact of Lactobacillus probiotics on lymph node responses to meningococcal vaccines in thirty male Albino rats with Streptozotocin-induced diabetes, established two weeks before vaccination. The diabetic rats were divided equally and randomly into three groups: one untreated (UD group), one receiving two shots of the meningococcal vaccine (DM group), and one receiving the same vaccination regimen alongside oral doses of

Indexed as

autoimmune proinflammatory cytokinesdiabetic diseasesIL-1βIL-2lymph nodesmeningococcal vaccineProbioticsTNF-α

Identifiers

PMID40689314
PMCPMC12267096

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.