Evidence map›Paper›PMID 40689293›Full record

ArticleCurrent research in food science2025

Identification of novel angiotensin I-converting enzyme inhibitory peptides from walnut (

Wenyun Xiong, Lixia Guo, Yiting Zhang, Shurui Li, Zihuan Wu, Shengbao Cai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current research in food science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenyun XiongFaculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming, Yunnan Province, People's Republic of China, 650500.
Lixia GuoFaculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming, Yunnan Province, People's Republic of China, 650500.
Yiting ZhangFaculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming, Yunnan Province, People's Republic of China, 650500.
Shurui LiFaculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming, Yunnan Province, People's Republic of China, 650500.
Zihuan WuFaculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming, Yunnan Province, People's Republic of China, 650500.
Shengbao CaiFaculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming, Yunnan Province, People's Republic of China, 650500.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to explore novel functional peptides derived from walnut protein isolate (WPI) that exhibited gastrointestinal stability, angiotensin I-converting enzyme (ACE1) inhibitory activity, and endothelial protective properties. Among the 81 detected peptides, 36 peptides with Glu, Leu, Pro, and Asp as the predominant residues were predicted to exhibit ACE1 inhibitory activity. Four promising peptides (TLEPT, TLEPN, VYLEQ, and VLSPQ) were selected for further evaluation based on predicted bioactivity and abundance.

Indexed as

ACE1 inhibitory peptidesGastrointestinal digestionHuman endothelial cellMolecular dockingMolecular dynamics simulationWalnut protein isolate

Identifiers

PMID40689293
PMCPMC12273483

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.