Evidence map›Paper›PMID 40689099›Full record

ArticleJournal of experimental orthopaedics2025

Infrapatellar fat pad fibrosis after anterior cruciate ligament reconstruction is associated with male sex, high body mass index, prolonged operation time and articular cartilage damage, with detrimental effects on one-year clinical outcomes.

Ryu Yoshida, Hideyuki Koga, Tomomasa Nakamura, Nobutake Ozeki, Mai Katakura, Masaki Amemiya, Takashi Hoshino, Aritoshi Yoshihara, Toyohiro Katsumata, Yasumasa Tokumoto and 2 more

Erratum issuedAbstract read
In one paragraph

Article in Journal of experimental orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Ryu YoshidaDepartment of Joint Surgery and Sports Medicine Institute of Science Tokyo Tokyo Japan.
Hideyuki KogaDepartment of Joint Surgery and Sports Medicine Institute of Science Tokyo Tokyo Japan.
Tomomasa NakamuraDepartment of Joint Surgery and Sports Medicine Institute of Science Tokyo Tokyo Japan.
Nobutake OzekiCenter for Stem Cell and Regenerative Medicine Institute of science Tokyo Tokyo Japan.
Mai KatakuraDepartment of Joint Surgery and Sports Medicine Institute of Science Tokyo Tokyo Japan.
Masaki AmemiyaDepartment of Joint Surgery and Sports Medicine Institute of Science Tokyo Tokyo Japan.
Takashi HoshinoDepartment of Joint Surgery and Sports Medicine Institute of Science Tokyo Tokyo Japan.
Aritoshi YoshiharaDepartment of Joint Surgery and Sports Medicine Institute of Science Tokyo Tokyo Japan.
Toyohiro KatsumataDepartment of Joint Surgery and Sports Medicine Institute of Science Tokyo Tokyo Japan.
Yasumasa TokumotoDepartment of Joint Surgery and Sports Medicine Institute of Science Tokyo Tokyo Japan.
Ichiro SekiyaCenter for Stem Cell and Regenerative Medicine Institute of science Tokyo Tokyo Japan.
Yusuke NakagawaDepartment of Joint Surgery and Sports Medicine Institute of Science Tokyo Tokyo Japan.ORCID https://orcid.org/0000-0003-0170-9743

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The aim of this study was to examine the risk factors of infrapatellar fat pad (IFP) fibrosis and the associations between the degree of IFP fibrosis and clinical outcomes in patients who underwent anterior cruciate ligament reconstruction (ACLR). Methods: A total of 97 patients who underwent primary ACLR using autologous hamstring tendons were divided into the mild fibrosis group (M group) and severe fibrosis group (S group), based on IFP fibrosis scoring (Grades 0-5) on magnetic resonance imaging at 3 months postoperatively. Clinical outcomes at 1 year postoperatively were compared between groups. Univariate logistic regression analysis was performed to determine factors associated with IFP fibrosis. Additionally, multiple linear regression analysis was performed to investigate whether IFP fibrosis affected clinical outcomes at 1 year postoperatively. Results: Patients were classified into the S group ( Conclusions: Male sex, high BMI, prolonged surgery, and articular cartilage damage are risk factors for IFP fibrosis after ACLR. IFP fibrosis affects the range of motion and subjective patient evaluations at 1 year postoperatively. MRI-based evaluation at 3 months may help identify high-risk patients, and early interventions targeting fibrosis could improve postoperative recovery. Level of Evidence: Level III, case-control study.

Indexed as

anterior cruciate ligament reconstructionclinical outcomesinfrapatellar fat pad fibrosismagnetic resonance imagingrisk factors

Identifiers

PMID40689099
PMCPMC12272509

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.