Evidence map›Paper›PMID 40689068›Full record

ArticleAnnals of translational medicine2025

The 6-methyladenine erasers ALKBH5 and FTO influence chemotherapy efficiency in bladder cancer cell lines.

Marie-Catherine Drigeard Desgarnier, Ida Monshaugen, Rune Ougland, Arne Klungland

Abstract read
In one paragraph

Article in Annals of translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. ALKBH5 promotes the progression of cisplatin-resistant oral squamous cell carcinoma by regulating FOXA1 expression via mDaru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marie-Catherine Drigeard DesgarnierDepartment of Microbiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.ORCID https://orcid.org/0000-0003-0755-6987
Ida MonshaugenDepartment of Microbiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.ORCID https://orcid.org/0000-0001-6276-6042
Rune OuglandDepartment of Microbiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.ORCID https://orcid.org/0000-0002-3108-7343
Arne KlunglandDepartment of Microbiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.ORCID https://orcid.org/0000-0001-7274-3661

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bladder cancer (BLCA) is a prevalent and life-threatening condition that significantly impacts patients' quality of life while imposing substantial financial costs on healthcare systems. Advancing our knowledge of the mechanisms underlying tumor development is crucial for improving treatment outcomes. Emerging studies emphasize the critical role of the RNA modification 6-methyladenine (m Methods: We first investigated the expression of Results: Lower expression of Conclusions: Our findings reveal that

Indexed as

6-methyladenine (m6A)Bladder cancer (BLCA)cisplatinerasersmitomycin (MMC)

Identifiers

PMID40689068
PMCPMC12272802

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.