Evidence map›Paper›PMID 40688983›Full record

ReviewCureus2025

Multidisciplinary Approaches to Limb Salvage in Traumatic Extremity Injuries From Emergency Triage to Definitive Vascular, Orthopedic, and Reconstructive Surgery: A Systematic Review.

Nabila Issa Youssouf, Huba Ali Khan, Asma Ahmed Osman Mohamed, Mohamed Bahaa Aboelsebaa Othman, Mahmoud Hassan Fadul Ismail, Ahmed A Hassan, Aliaa H Alkhazendar, Jarallah H J Alkhazendar, Monezahe Zehra, Deewan Aakash

RetractedAbstract readReviewRetracted Publication
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Nabila Issa YoussoufSurgery, International University of Africa, Khartoum, SDN.
Huba Ali KhanEmergency Medicine, Ziauddin University, Karachi, PAK.
Asma Ahmed Osman MohamedSurgery, Burjeel Medical City, Abu Dhabi, SAU.
Mohamed Bahaa Aboelsebaa OthmanVascular Surgery, Nasser Institute Hospital for Research and Treatment, Cairo, EGY.
Mahmoud Hassan Fadul IsmailInternational Public Health, Royal Infirmary of Edinburgh, Edinburgh, GBR.
Ahmed A HassanOrthopedics and Trauma, Suez Canal University Hospital, Ismailia, EGY.
Aliaa H AlkhazendarSurgery, Islamic University of Gaza, Gaza, PSE.
Jarallah H J AlkhazendarGeneral and Emergency Surgery, East and North Hertfordshire NHS Trust, Lister Hospital, Stevenage, GBR.
Monezahe ZehraSurgery, Abbasi Shaheed Hospital, Karachi, PAK.
Deewan AakashSurgery, Liaquat National Hospital, Karachi, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review explores the impact of multidisciplinary team (MDT) approaches in the management of complex limb injuries, comparing limb salvage and amputation outcomes across diverse trauma settings. Drawing from six recent studies involving both acute and chronic extremity trauma, the findings highlight consistent benefits of coordinated care involving orthopedic, vascular, and plastic surgery specialties. These include reduced flap loss, faster time to definitive fixation, improved functional recovery, and enhanced decision-making regarding salvage versus amputation. While functional and psychological outcomes following salvage and amputation were often comparable, early MDT involvement improved wound healing and lowered short-term mortality rates in select patient groups. Variability in outcomes was influenced by institutional resources, timing of intervention, and patient comorbidities. Scoring systems such as the Mangled Extremity Severity Score (MESS) and the Mangled Extremity Syndrome Index (MESI) aided but did not replace clinical judgment. Overall, the integration of multidisciplinary pathways into trauma care enhances outcome quality and supports patient-centered decision-making in complex limb trauma cases.

Indexed as

amputationcomplex extremity traumalimb reconstructionlimb salvagemangled limbmultidisciplinary teamorthoplastic surgerytrauma managementtrauma surgery outcomesvascular surgery

Identifiers

PMID40688983
PMCPMC12271822

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.