Evidence map›Paper›PMID 40688960›Full record

ArticleCureus2025

Multiple Myeloma Presenting With Sudden Paraplegia.

Hugo Veiga, Manuel Almeida, Pedro Duarte, José Artur Paiva, Elisabete Monteiro

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hugo VeigaIntensive Care Department, Hospital de São João, Porto, PRT.
Manuel AlmeidaIntensive Care Department, Hospital de Portimão, Portimão, PRT.
Pedro DuarteIntensive Care Department, Hospital Divino Espírito Santo, Ponta Delgada, PRT.
José Artur PaivaIntensive Care Department, Hospital de São João, Porto, PRT.
Elisabete MonteiroIntensive Care Medicine Department, Hospital de São João, Porto, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma (MM) is a malignant neoplasia predominantly characterized by systemic manifestations, but atypical presentations can challenge diagnosis and management, as in the case of solitary plasmacytoma. We present a case of a 60-year-old woman with sudden paraplegia due to a solitary dorsal spinal mass compressing the spinal cord. Emergent surgical decompression prevented further neurological deterioration, but permanent paraplegia remained. This case underlines the importance of recognizing atypical presentations of multiple myeloma, such as solitary spinal lesions, which may mimic other conditions. Early diagnosis and intervention are crucial to prevent irreversible neurological sequelae. Prompt surgical decompression, followed by systemic therapy, can optimize outcomes in patients with this pathology. Multidisciplinary collaboration and aggressive management of complications, as well as early rehabilitation, are also essential to address the complex needs of these patients and improve outcomes.

Indexed as

dorsal spinal massextra-medullary plasmacytomamedullary syndromemultiple myelomaparaplegia

Identifiers

PMID40688960
PMCPMC12276642

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.