ArticleCureus2025
Clinical- and Device-Related Factors Associated With Atrial High Rate Episodes in Patients With Dual-Chamber Pacemakers.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Incremental predictive value of device and echocardiographic parameters for atrial high-rate episodes: a prospective cohort study.BMC cardiovascular disorders · 2026Article
- Predictors for Device-Detected Subclinical Atrial Fibrillation: An Up-to-Date Narrative Review.Journal of clinical medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction Atrial high-rate episodes (AHREs) detected by dual-chamber pacemakers may represent subclinical precursors of atrial fibrillation and thromboembolic events. However, the clinical-, electrocardiographic-, and device-related characteristics distinguishing patients with and without AHREs are not fully defined. This study aimed to compare these variables between both groups to identify those independently associated with the presence of AHREs. Methods This retrospective, single-center observational study included ambulatory patients with dual-chamber pacemakers evaluated between June and December 2024. Clinical, electrocardiographic, and device-related variables were compared between patients with and without AHREs. Bivariate analyses were conducted to identify significant differences, and multivariable logistic regression was used to determine variables independently associated with the presence of AHREs. Results A total of 450 individuals were included, of whom 185 (41.1%) exhibited AHREs, compared to 265 (58.9%) without AHREs, those affected were more frequently female, 116 (62.7%) versus 140 (52.8%), p = 0.037, and had a higher prevalence of prior atrial fibrillation or atrial tachycardia, 98 (53.0%) versus 68 (25.7%), p < 0.001. Ventricular pacing was slightly lower in the AHRE group (median 98% vs. 99%; p = 0.016), and atrial pacing mode with switch to dual-chamber (AAI-DDD) pacing mode was more common, 44 (23.8%) versus 32 (12.1%), p = 0.001. In multivariable analysis, prior atrial arrhythmias (OR 2.95; p < 0.001), follow-up ≥ 90 days (OR 4.14; p = 0.012), female sex (OR 1.63; p = 0.020), and AAI-DDD pacing (OR 1.92; p = 0.027) were independently associated with AHREs. The model demonstrated acceptable discrimination (area under the curve (AUC) = 0.70). Conclusion In this cohort, AHREs were observed in 41.1% of participants. Their occurrence was significantly associated with female sex, a prior history of atrial fibrillation or atrial tachycardia, a follow-up duration of 90 days or more, reduced ventricular pacing, and the use of the AAI-DDD pacing mode.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.