ArticleCureus2025
Exploring the Rare Hobnail Variant of Papillary Thyroid Carcinoma: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The hobnail variant of papillary thyroid carcinoma (HPTC) is a rare but highly aggressive form of thyroid cancer, associated with a more severe clinical course and significantly poorer prognosis compared to conventional PTC. To be classified as HPTC, a tumor must contain at least 30% of cells exhibiting hobnail-micropapillary features. These cells are characterized by distinctive papillary cytomorphology, including a hobnail-like appearance, the presence of papillae and micropapillae, high nuclear-to-cytoplasmic ratios, apically located nuclei, and prominent nucleoli. Additionally, some studies have reported associations between HPTC and specific genetic mutations, such as BRAFV600E, TP53, and TERT. In this article, we present the case of a 58-year-old male diagnosed with HPTC, managed with radiotherapy.
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