ArticleCureus2025
Protective Factors Against Hypertension: A Retrospective Population-Based Analysis of Resilience in High-Risk Groups.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background While risk factors for hypertension (HTN) are well-known, some high-risk individuals remain free of the condition, suggesting the presence of protective factors. Objective The objective of this study is to identify protective factors associated with resistance to hypertension among high-risk individuals using National Health and Nutrition Examination Survey (NHANES) data. Methods A retrospective, cross-sectional analysis was conducted using NHANES data from 2007 to 2018. Multivariable logistic regression was used to examine the links between hypertension and possible protective factors such as high-density lipoprotein (HDL) cholesterol, sleep duration, and dietary fiber intake (DFI) while taking into account age, gender, and race/ethnicity. Results Higher HDL cholesterol and longer sleep duration were significantly associated with reduced odds of hypertension. Dietary fiber intake was not independently associated after adjustment. Conclusion HDL cholesterol and adequate sleep appear to offer protective effects against hypertension. Further studies should include genetic markers, inflammatory biomarkers, and omega-3 fatty acids to better understand biological resilience to hypertension.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.