Evidence map›Paper›PMID 40688874›Full record

ArticleCureus2025

Progressive Cranial Nerve Deficits in Granulomatosis With Polyangiitis: A Case Report.

Ryan Waggoner, Imran Bitar, Manasa Pavuloori, Atheel Yako, Natasha Kizy

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ryan WaggonerSchool of Medicine, Oakland University William Beaumont School of Medicine, Rochester, USA.
Imran BitarSchool of Medicine, Oakland University William Beaumont School of Medicine, Rochester, USA.
Manasa PavulooriSchool of Medicine, Oakland University William Beaumont School of Medicine, Rochester, USA.
Atheel YakoNeurology, Corewell Health William Beaumont University Hospital, Royal Oak, USA.
Natasha KizyNeurology, Corewell Health William Beaumont University Hospital, Royal Oak, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Granulomatosis with polyangiitis (GPA) is a rare systemic vasculitis that can involve multiple organ systems, including the nervous system. Central nervous system (CNS) involvement, especially in the form of cranial nerve neuropathy, is uncommon and may present with significant diagnostic challenges. This case report details the presentation, diagnostic workup, and management of a 60-year-old female who initially developed unilateral cranial nerve deficits, which progressed to bilateral involvement over an 11-day hospital course. The purpose of this case report is to highlight the importance of including GPA in the differential diagnosis in the setting of progressive cranial neuropathy, and to emphasize the need for a multidisciplinary approach for timely diagnosis and utilization of immunosuppressive treatment to minimize the chronic effects of the disease.

Indexed as

anca-associated vasculitiscranial nerve involvementgranulomatosis with polyangiitis (gpa)multidisciplinary diagnosisneuroimmunologysystemic autoimmune disease

Identifiers

PMID40688874
PMCPMC12276022

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.