ReviewCureus2025
Evidence-Based Topical Therapy for Facial Scars in Diverse Skin Types.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Comparative efficacy and safety of fractional carbon dioxide and erbium-based fractional lasers for atrophic acne scars: A systematic review and meta-analysis.Lasers in medical science · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Facial trauma repair frequently results in scarring that can significantly impact psychological well-being, particularly in highly visible areas, such as the face. While topical agents provide a non-invasive means of optimizing scar outcomes, clinical guidance regarding their use remains limited, especially for diverse skin types. This narrative review synthesizes findings from PubMed, Google Scholar, and Embase, prioritizing randomized controlled trials, meta-analyses, and expert consensus. Evidence supports the use of silicone gel, corticosteroids, retinoids, vitamin C, niacinamide, and onion extract for scar modulation. A timeline-based model was developed to guide agent selection across healing phases, emphasizing early intervention after re-epithelialization and tailored regimens for patients with Fitzpatrick skin types IV-VI. This review proposes a phase-specific approach to facial scar optimization that integrates skin phototype considerations. Further research is needed to validate the safety and efficacy of combinatory topical regimens across diverse populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.