Evidence map›Paper›PMID 40688846›Full record

ArticleCureus2025

Association Between Perceived Stress and Fatigue Severity in Patients With Chronic Illnesses.

Vaisnavy Govindasamy, Marium Nadeem Khan, Zeeshan Khalid Awan, Abali Wandala, Muhammad Bilal Akbar, Aaleen Kamran, Mohamed Attian, Warda Shahbaz, Abeeha Mahmood, Meera Al Shamsi and 1 more

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Vaisnavy GovindasamyMedicine, South Tees NHS Trust, Middlesbrough, GBR.
Marium Nadeem KhanMedicine, Shifa College of Medicine, Islamabad, PAK.
Zeeshan Khalid AwanCollege of Medicine, MindWave Research Center, Islamabad, PAK.
Abali WandalaInterventional Cardiology, Mission Vascular and Vein Institute, Mission, USA.
Muhammad Bilal AkbarPsychiatry, Tallaght University Hospital, Dublin, IRL.
Aaleen KamranPathology, Foundation University Medical College, Islamabad, PAK.
Mohamed AttianSurgery, Milton Keynes University Hospital, Milton Keynes, GBR.
Warda ShahbazMedicine, University Hospital Southampton, NHS Foundation Trust, Southampton, GBR.
Abeeha MahmoodMedicine, Combined Military Medical College and Hospital, Lahore, PAK.
Meera Al ShamsiInternal Medicine, Zayed Higher Organization for People of Determination, Abu Dhabi, ARE.
Zill-E-Rukh Fatima AmeerMedicine, Combined Military Medical College and Hospital, Lahore, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStress and fatigue are two of the most important contributing factors to the declining physical and mental well-being of patients suffering from chronic illnesses. This research aims to identify the direct relationship between stress and fatigue to improve treatment guidelines and patient care. METHODOLOGY: This observational study was conducted from February to April 2025 in Islamabad, Pakistan. The study included adults over 18 years of age, individuals who provided consent, and those diagnosed with chronic illnesses such as diabetes, cardiovascular disease, autoimmune disorders, or cancer. A questionnaire was used to collect data comprising the Perceived Stress Scale and Fatigue Severity Scale. Analysis was performed through IBM SPSS Statistics for Windows, Version 26 (Released 2018; IBM Corp., Armonk, New York, United States).

resultsAround 181 participants (47%) were male, 165 (43%) were female, and 40 individuals (10%) preferred not to disclose their gender. The largest age group was 26-35 years, with 240 individuals (62%), followed by 69 participants (18%) aged 36-45 years. The most commonly reported condition was hypertension, affecting 125 individuals (32%), followed by cardiovascular disease in 114 participants (29%) and diabetes in 57 (15%). A statistically significant moderate positive correlation between stress and fatigue (r = 0.481, p < 0.01) was obtained.

conclusionA strong positive correlation exists between perceived stress and fatigue severity among individuals with chronic diseases, influenced by factors like sleep duration and time since diagnosis.

Indexed as

chronic illnessfatigue severityperceived stresspsychological well-beingsleep duration

Identifiers

PMID40688846
PMCPMC12276770

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.