Evidence map›Paper›PMID 40688759›Full record

ArticleBiofilm2025

Antimicrobial efficacy of on-label vs. hand-mixed irrigation solutions against

Robert Falconer, Tyler Smith, David Rothberg, Jeremy Gililland, Nicholas Ashton, Dustin Williams

Abstract read
In one paragraph

Article in Biofilm, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Robert FalconerDepartment of Orthopaedics, University of Utah, Salt Lake City, UT, 84108, USA.
Tyler SmithDepartment of Orthopaedics, University of Utah, Salt Lake City, UT, 84108, USA.
David RothbergDepartment of Orthopaedics, University of Utah, Salt Lake City, UT, 84108, USA.
Jeremy GilillandDepartment of Orthopaedics, University of Utah, Salt Lake City, UT, 84108, USA.
Nicholas AshtonDepartment of Orthopaedics, University of Utah, Salt Lake City, UT, 84108, USA.
Dustin WilliamsDepartment of Orthopaedics, University of Utah, Salt Lake City, UT, 84108, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound irrigation is routinely performed as part of the DAIR procedure and for hardware infections, yet the most effective irrigation solution for reducing bacterial bioburden is unknown. Clinicians can choose on-label, commercially available irrigation solutions or hand-mix preparations off-label on the operating back table. Current methods for evaluating antiseptic efficacy often do not represent the clinical scenario. Here, we present a proof-of-concept

Indexed as

BiofilmChlorhexidineInfectionPovidone-iodineStaphylococcus aureusTrauma

Identifiers

PMID40688759
PMCPMC12275869

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.