Evidence map›Paper›PMID 40688751›Full record

ArticleCancer management and research2025

The Chain Mediating Role of Hope and Posttraumatic Growth Between Social Support and Psychological Distress Among Lung Cancer Patients.

Jin-Gui Huang, Chen-Han Xu, Yu-Mei Shi, Juan Jiang, Feng-Mei Huang, Ling-Li Xu

Abstract read
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Article in Cancer management and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. From rumination quagmire to hope's flame: a cross-sectional mediation study of family support and life satisfaction among hematological cancer caregivers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jin-Gui Huang *Department of Medical Oncology, Chongqing University Cancer Hospital, Chongqing, 400030, People's Republic of China.
Chen-Han Xu *College of Computer Science, Chongqing University, Chongqing, 400000, People's Republic of China.
Yu-Mei ShiDepartment of Medical Oncology, Chongqing University Cancer Hospital, Chongqing, 400030, People's Republic of China.
Juan JiangDepartment of Gastroenterology, Chongqing University Cancer Hospital, Chongqing, 400030, People's Republic of China.
Feng-Mei HuangDepartment of Medical Oncology, Chongqing University Cancer Hospital, Chongqing, 400030, People's Republic of China.ORCID 0000-0001-9595-7304
Ling-Li XuDepartment of Human Resources, Chongqing University Cancer Hospital, Chongqing, 400030, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This research was designed to explore whether hope and posttraumatic growth (PTG) played a mediating role between social support and psychological distress in patients diagnosed with lung cancer. Patients and Methods: A hospital-based cross-sectional study was carried out on 502 lung cancer patients. From September 2023 to April 2024, participants were recruited via convenience sampling from one tertiary cancer hospital and two tertiary general hospitals in Chongqing, China. Patients completed questionnaires on demographics, medical information, Distress thermometer, Perceived Social Support Scale, Posttraumatic Growth Inventory, and Herth Hope Index. Statistical analyses included Pearson's chi-squared test or Fisher's exact test for differences in patient characteristics by psychological distress level. Pearson correlation analysis explored relationships among variables. Bootstrapping in structural equation modeling (SEM) evaluated structural paths, and multi-group SEM analysis tested the moderating effect of gender. Results: 43.6% (219/502) of lung cancer patients experience psychological distress. After controlling for cancer stage and distant metastasis, the results suggested that social support had a negative direct effect on psychological distress. In addition, social support could also influence psychological distress via three pathways: (1) the mediating effect of hope, (2) the mediating effect of PTG, and (3) the serial mediating effect of hope and PTG. The indirect effect of the three intermediary paths accounted for 72.7% of the total effect. Gender moderated the effect of social support on PTG ( Conclusion: This study found that lung cancer patients exhibit high levels of psychological distress. Social support directly impacts psychological distress and acts through multiple pathways: the mediating effects of hope and PTG, as well as their serial mediation. These findings deepen our understanding of how social support affects psychological distress in lung cancer patients and its underlying mechanisms, providing empirical support for developing interventions to alleviate distress.

Indexed as

hopelung cancerposttraumatic growthpsychological distressserial mediation modelsocial support

Identifiers

PMID40688751
PMCPMC12276738

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.