Evidence map›Paper›PMID 40688673›Full record

ReviewMaterials today. Bio2025

Stimuli-responsive nanozymes for wound healing: From design strategies to therapeutic advances.

Yu Wei, Wanchun You, Haiqing Li, Jiawen Chen, Ziyi Tang, Yawen Luo, Wantong Xiao, Qianwen Yang, Meixin Feng, Li Li and 1 more

Abstract readReview
In one paragraph

Review in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Immunomodulatory Nanozymes as Programmable Redox-Immune Set-Point Regulators.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. The Role and Mechanism of Nanozymes in Burn Wound Healing.International journal of nanomedicine · 2026
    Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yu WeiDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Wanchun YouDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Haiqing LiDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Jiawen ChenDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Ziyi TangDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Yawen LuoDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Wantong XiaoDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Qianwen YangDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Meixin FengDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Li LiDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Menglei WangDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanozymes, which mimic the activity of natural enzymes, have demonstrated significant advantages in wound healing. Stimuli-responsive nanozymes, a novel design type developed recently, are capable of on-demand targeted release, catalytic activity modulation, and facilitating synergistic therapeutic strategies. Such advancements further enhance the safety and efficacy of nanozyme-based treatments. Although numerous studies have reported their high efficiency in promoting wound healing, there remains a lack of updated review literature on this topic. This paper starts by exploring the design strategies of advanced stimuli-responsive nanozymes (including types responsive to pH, glucose, enzyme, light, ultrasound, and magnetic fields), providing a comprehensive analysis of their underlying mechanisms, while highlighting their application progress across diverse wound types. Furthermore, this paper provides a forward-looking perspective on the future development of stimuli-responsive nanozymes.

Indexed as

Catalytic activity modulationStimuli-responsive nanozymesSynergistic therapyTherapeutic efficacyWound healing

Identifiers

PMID40688673
PMCPMC12275949

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.