ArticleInternational journal of general medicine2025
Paroxysmal Sympathetic Hyperactivity, Volume Status, and Neurological Prognosis in Acute Brain Injury: A Prospective Cohort Analysis.
Article in International journal of general medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: In this study, we enrolled patients with acute brain injury (ABI) to examine the relationship between paroxysmal sympathetic hyperactivity (PSH) and volume status, right heart function, and pulmonary edema, and their impact on prognosis. Methods: Thirty patients with ABI were prospectively enrolled. A correlation analysis between Paroxysmal Sympathetic Hyperactivity Assessment Measure (PSH-AM) score and clinical indicators was performed using Pearson's or Spearman correlation coefficient. Receiver operating characteristic (ROC) curves were used to assess the prediction of 6-month Glasgow Outcome Scale Extended (GOSE) score. Inferior vena cava (IVC) diameter was evaluated as a marker of intravascular volume status, and its correlation with 6-month GOSE score in ABI patients was analyzed. Results: There was no statistically significant difference in PSH-AM over time in patients with ABI ( Conclusion: IVC diameter assessed on day 1 is a useful indicator of neurological prognosis in patients with ABI. There was no statistically significant difference in PSH over time in patients with ABI. Regarding the study's sample size and potential operator bias in IVC diameter measurement, the findings require validation in larger, multicenter studies with standardized measurement protocols.
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