ArticleIDCases2025
Alopecia as the initial presentation of secondary syphilis: A case report and review of literature.
Article in IDCases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Syphilitic alopecia is a rare cutaneous manifestation of secondary syphilis. It is described as a non-scarring hair loss which usually presents as the pathognomonic moth-eaten pattern. Syphilis-associated alopecia often mimics that of other types of hair loss, which may lead to misdiagnosis or delay in treatment. Herein, we present a case of a 29-year-old man who presented with hair loss and pruritic painless scalp lesions. His history was unremarkable except for another sexually transmitted infection two years ago, along with sexual contact two months prior to his current presentation. Diagnosis of secondary syphilis was confirmed through serological tests. Hair regrowth was achieved within approximately three months following penicillin treatment. The present case highlights the strong clinical acumen required to diagnose secondary syphilis in a patient presenting with alopecia, particularly when it is the only initial presenting symptom.
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