Evidence map›Paper›PMID 40688423›Full record

ArticleIDCases2025

A case of acute abdomen caused by visceral disseminated varicella-zoster virus infection causes diagnostic challenges during the course of systemic lupus erythematosus.

Koki Matsushita, Yu Nagayoshi, Ryosuke Yamamura, Keishi Nakamura, Yutaka Kakizoe, Yuichiro Izumi, Masataka Adachi, Masashi Mukoyama, Hideki Yokoi

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in IDCases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Koki MatsushitaDepartment of Nephrology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, Japan.
Yu NagayoshiDepartment of Nephrology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, Japan.
Ryosuke YamamuraDepartment of Nephrology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, Japan.
Keishi NakamuraDepartment of Nephrology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, Japan.
Yutaka KakizoeDepartment of Nephrology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, Japan.
Yuichiro IzumiDepartment of Nephrology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, Japan.
Masataka AdachiDepartment of Nephrology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, Japan.
Masashi MukoyamaDepartment of Nephrology, Omuta Tenryo Hospital, 1-100, Tenryomachi Omuta, Fukuoka, Japan.
Hideki YokoiDepartment of Nephrology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Visceral disseminated varicella-zoster virus (VD-VZV) infection, resulting from primary infection by, or reactivation of, VZV, is a rare and severe complication in immunosuppressed patients. Because VD-VZV often develops alongside acute abdominal pain, which precedes appearance of the skin rash, diagnosis is difficult. Here, we report a case of 48-year-old woman who presented with acute abdomen, leading to a diagnosis of VD-VZV infection. The patient developed systemic lupus erythematosus 4 months earlier, and had been treated with immunosuppressants. The patient was treated successfully with a 7-day course of intravenous acyclovir. VD-VZV infection should be considered as a differential diagnosis in immunosuppressed patients with acute abdomen. Early diagnosis and prompt treatment with antivirals are crucial for improved patient outcomes.

Indexed as

Acute abdomenSystemic lupus erythematosusVisceral disseminated varicella-zoster virus

Identifiers

PMID40688423
PMCPMC12274684

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.