Evidence map›Paper›PMID 40688228›Full record

ReviewTranslational pediatrics2025

Ureteral clipping for managing persistent urinary dribbling caused by ectopic ureters associated with non-functioning renal moieties in girls with complex duplex kidneys: a narrative review of the literature.

Giulia Lanfranchi, Irene Paraboschi, Guglielmo Mantica, Sara Costanzo, Giorgio Giuseppe Orlando Selvaggio, Manuel Lopez, Gloria Pelizzo

Abstract readReview
In one paragraph

Review in Translational pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giulia LanfranchiDepartment of Pediatric Surgery, "V. Buzzi" Children's Hospital, Milan, Italy.
Irene ParaboschiDepartment of Pediatric Surgery, "V. Buzzi" Children's Hospital, Milan, Italy.
Guglielmo ManticaDepartment of Surgical and Diagnostic Integrated Sciences (DISC), University of Genova, Genoa, Italy.
Sara CostanzoDepartment of Pediatric Surgery, "V. Buzzi" Children's Hospital, Milan, Italy.
Giorgio Giuseppe Orlando SelvaggioDepartment of Pediatric Surgery, "V. Buzzi" Children's Hospital, Milan, Italy.
Manuel LopezDepartment of Pediatric General and Urogenital Surgery, Vall d'Hebron Hospital, Barcelona, Spain.
Gloria PelizzoDepartment of Pediatric Surgery, "V. Buzzi" Children's Hospital, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objective: Persistent urinary dribbling in girls with duplex renal systems and ectopic ureters originating from poorly functioning renal moieties represents a complex clinical problem in pediatric urology. The incontinence associated with these anomalies is socially distressing and often refractory to conservative management. Traditional surgical options, including upper pole heminephrectomy or ureteroureterostomy, are effective but may be associated with significant operative morbidity, particularly when renal function is negligible and surgical access is challenging. In recent years, minimally invasive ureteral ligation-either laparoscopic or via open mini-incision-has emerged as a promising, low-risk alternative to excise or disconnect the ectopic ureter. This review article aims to critically evaluate the safety, efficacy, and clinical utility of ureteral ligation in this subset of pediatric patients. Methods: A comprehensive literature search was conducted using PubMed and Web of Science through May 2024. Keywords included "ureteral clipping", "ureteral ligation", "ectopic ureter", and "paediatric urinary incontinence". Only English-language studies involving human pediatric populations were considered. Exclusion criteria included duplicate publications, animal studies, and articles that did not report clinical outcomes. Two independent reviewers performed data extraction and synthesis, focusing on postoperative continence, complications, renal outcomes, and procedural details. Key Content and Findings: Ureteral ligation was consistently associated with resolution or significant improvement of urinary incontinence in girls with ectopic ureters and non-functional upper moieties. The procedure appears to be technically straightforward, with minimal operative time and negligible intraoperative blood loss. Complication rates were low, and only one case of subsequent symptomatic infection or functional loss in the remaining renal moiety were reported. However, available data derive predominantly from small, retrospective, single-center series, with limited follow-up durations and the absence of control groups. Conclusions: Minimally invasive ureteral ligation represents a viable and effective surgical option for selected patients with ectopic ureters draining poorly functioning renal segments. Larger, multicenter prospective studies are warranted to confirm its long-term efficacy and establish clear clinical guidelines for its broader adoption.

Indexed as

childrenduplex kidneyectopic ureterincontinenceUreteral clipping

Identifiers

PMID40688228
PMCPMC12268618

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.