Evidence map›Paper›PMID 40688188›Full record

ArticleCardiovascular therapeutics2025

Astragaloside IV Alleviates H

Miaomiao Qi, Qiongying Wang, Runmin Sun, Zeyi Cheng, Mingze Li, Xin Fan, Feng Bai, Jing Yu

Abstract read
In one paragraph

Article in Cardiovascular therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Miaomiao QiDepartment of Cardiology, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China.ORCID https://orcid.org/0009-0004-5116-7617
Qiongying WangDepartment of Cardiology, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China.ORCID https://orcid.org/0000-0002-5497-3196
Runmin SunDepartment of Cardiology, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China.
Zeyi ChengDepartment of Cardiac Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Mingze LiThe Second Clinical Medical School of Lanzhou University, Lanzhou University, Lanzhou, Gansu Province, China.
Xin FanDepartment of Cardiology, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China.
Feng BaiDepartment of Cardiology, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China.
Jing YuDepartment of Cardiology, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China.ORCID https://orcid.org/0000-0002-4164-764X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress and mitochondrial dysfunction play critical roles in the pathology of cardiovascular diseases. However, the effects of Astragaloside IV (As-IV) on mitochondrial function remain unclear. This study is aimed at evaluating the protective effects and mechanism of As-IV against H

Indexed as

Hydrogen PeroxideMitochondria, HeartMitophagyMyocytes, CardiacPhosphatidylinositol 3-KinaseProto-Oncogene Proteins c-aktSaponinsTOR Serine-Threonine KinasesTriterpenesAnimalsApoptosisCell LineMembrane Potential, MitochondrialMitochondrial DynamicsOxidative StressProtein Kinasesastragaloside AHydrogen PeroxidemTOR protein, ratparkin proteinPhosphatidylinositol 3-KinaseProtein KinasesProto-Oncogene Proteins c-aktPTEN-Induced Putative KinaseReactive Oxygen SpeciesSaponinsTOR Serine-Threonine KinasesTriterpenesUbiquitin-Protein LigasesAstragaloside IVmitochondrial dysfunctionmitophagyoxidative stressPI3K/AKT/mTOR

Identifiers

PMID40688188
PMCPMC12271723

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.