Evidence map›Paper›PMID 40688164›Full record

ArticleThe Lancet regional health. Western Pacific2025

Prevalence of germline

Hee Kyung Ahn, Jee Hung Kim, Su-Jin Koh, Joohyuk Sohn, Myoung Joo Kang, Kyung Hae Jung, Kyoung Eun Lee, Jieun Lee, Sung Ae Koh, Yee Soo Chae and 12 more

Abstract read
In one paragraph

Article in The Lancet regional health. Western Pacific, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Associations between multiple essential trace metal concentrations and risk of hyperuricemia: insights from a central Chinese population.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Hee Kyung AhnDivision of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Republic of Korea.
Jee Hung KimDivision of Medical Oncology, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Republic of Korea.
Su-Jin KohDepartment of Hematology and Oncology, Ulsan University Hospital, Ulsan University College of Medicine, Republic of Korea.
Joohyuk SohnDivision of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, College of Medicine, Yonsei University, Republic of Korea.
Myoung Joo KangDivision of Oncology, Department of Internal Medicine, Inje University College of Medicine, Haeundae Paik Hospital, Republic of Korea.
Kyung Hae JungDepartment of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Republic of Korea.
Kyoung Eun LeeDivision of Hematology/Oncology, Department of Internal Medicine, School of Medicine, Ewha Womans University, Republic of Korea.
Jieun LeeDivision of Medical Oncology, Department of Internal Medicine, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Republic of Korea.
Sung Ae KohDepartment of Internal Medicine, Yeungnam University College of Medicine, Republic of Korea.
Yee Soo ChaeDepartment of Internal Medicine, Kyungpook National University Chilgok Hospital, Republic of Korea.
Jae Ho ByunDivision of Medical Oncology, Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea.
In Hae ParkDepartment of Hemato-Oncology, Division of Internal Medicine, Korea University College of Medicine, Guro Hospital, Republic of Korea.
Hee-Jun KimDepartment of Internal Medicine, Chung-Ang University College of Medicine, Republic of Korea.
Jee Hyun KimDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Republic of Korea.
Han Jo KimDivision of Oncology and Hematology, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Republic of Korea.
Joo Young JungDepartment of Internal Medicine, Hallym University Medical Center, Hallym University College of Medicine, Republic of Korea.
Jung Lim LeeDivision of Hematology & Medical Oncology, Department of Internal Medicine, Daegu Fatima Hospital, Republic of Korea.
Yoon Young ChoDepartment of Hematology Oncology, Daegu Catholic University Medical Center, Republic of Korea.
Kyong Hwa ParkDivision of Medical Oncology and Hematology, Department of Internal Medicine, Korea University Anam Hospital, Republic of Korea.
Ji-Yeon KimDivision of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Republic of Korea.
Seock-Ah ImDepartment of Internal Medicine, Cancer Research Institute, College of Medicine, Seoul National University Hospital, Seoul National University, Republic of Korea.
Yeon Hee ParkDivision of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Assessment of germline (g) Methods: Patients diagnosed with HER2-negative metastatic BC receiving palliative systemic treatment were eligible for inclusion in the study. Peripheral blood was prospectively drawn from each patient and g Findings: A total of 586 patients were enrolled between October 2019 and March 2022, and the prevalence of g Interpretation: Our study measured the size of the current underestimation of g Funding: Pfizer.

Indexed as

BRCA1BRCA2Breast cancerChemotherapyPrevalence

Identifiers

PMID40688164
PMCPMC12272606

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.