Evidence map›Paper›PMID 40688088›Full record

ReviewFrontiers in immunology2025

Chronic central nervous system aspergillosis with coexisting GFAP and AQP4 antibody positivity: case report and literature review.

Yimin Cao, Xueying Zhao, Shengpu Hao, Haiqing Yang, Duo Gao, Shixuan Du, Liang Wang, LiXia Zhou

Abstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yimin CaoDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Xueying ZhaoDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Shengpu HaoDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Haiqing YangDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Duo GaoDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Shixuan DuDepartment of Pathology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Liang WangDepartment of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
LiXia ZhouDepartment of Medical Imaging, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article presents an unusual case of chronic central nervous system (CNS) aspergillosis with concurrent glial fibrillary acidic protein (GFAP)-IgG and aquaporin-4 (AQP4)-IgG seropositivity. The patient presented with progressive numbness and weakness of the extremities over three months. The diagnosis was established by a cell-based assay demonstrating double positivity for GFAP-IgG and AQP4-IgG; imaging revealed multiple foci in the right temporo-occipital lobe and cervical medulla. Surgical pathology confirmed parenchymal

Indexed as

Aquaporin 4AutoantibodiesGlial Fibrillary Acidic ProteinNeuroaspergillosisChronic DiseaseHumansImmunoglobulin GAQP4 protein, humanAquaporin 4AutoantibodiesGFAP protein, humanGlial Fibrillary Acidic ProteinImmunoglobulin Gaquaporin-4 antibodyautoimmune antibodiescentral nervous system aspergillosisglial fibrillary acidic protein antibodyimmunity

Identifiers

PMID40688088
PMCPMC12271150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.