ReviewInternational journal of pharmaceutics: X2025
Ionic liquids self-assembled micelles for transdermal delivery: characterization, functions and applications.
Review in International journal of pharmaceutics: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Ionic Liquids as Interfacial Media for Metal-Free Electrochemical COACS sustainable chemistry & engineering · 2026Article
- Ionic Liquids in the Aza-Michael Reaction: From Early Imidazolium Salts to Bio-Based Catalytic Media.Molecules (Basel, Switzerland) · 2026Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ionic liquid (ILs) self-assembled micelles (ILs-SAMs) are promising and effective drug delivery systems, which combine the merits of ILs and micelles. Herein, the properties, assembly, functions, and treatments of ILs-SAMs in transdermal drug delivery are summarized. This paper first reviews the fundamental concepts, classifications, assembly mechanisms, characterization techniques, and functional roles of ILs-SAMs. ILs-SAMs are micellar structures formed by the self-assembly of ILs through different intermolecular interactions, and are affected by multiple environmental factors. They possess unique physicochemical properties, endowing them with high stability and effective drug carriers, which could regulate their compositions and structures for flexible and controllable characteristics. Next, the review demonstrates that ILs-SAMs offer remarkable advantages in transdermal delivery, including solubilization enhancement, permeation enhancement, and targeted transdermal delivery. It alters the surface tension and viscosity of permeating substances, facilitates transdermal drug penetration, and utilizes nanoscale properties for precise, targeted delivery. Remarkably, ILs-SAMs were compared with other ILs self-assembled nanoparticles (ILs-SANPs) and polymer micelles, and the former possessed superior properties, including easier self-assembly and higher stability. Lastly, it focuses on their applications in treating skin cancer, arthritis, diabetes, fungal infections, and skin photoaging. Collectively, the novel ILs-SAMs are multifunctional transdermal drug delivery systems used for permeation enhancement, targeted drug delivery and different skin disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.