Evidence map›Paper›PMID 40688022›Full record

ArticleBioactive materials2025

An injectable and dual-crosslinked hydrogel for controlled and permanent vascular embolization.

Xin Wang, Hantao Yang, Yaoben Wang, Yang Wang, Xuanbo Hu, Jiaxin Huang, Zhiyong Chen, Yu Chen, Jiandong Ding, Lin Yu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xin WangState Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, 200438, China.
Hantao YangShanghai Geriatric Medical Center, 2560 Chunshen Road, Shanghai, 201104, China.
Yaoben WangState Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, 200438, China.
Yang WangState Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, 200438, China.
Xuanbo HuState Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, 200438, China.
Jiaxin HuangState Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, 200438, China.
Zhiyong ChenState Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, 200438, China.
Yu ChenState Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, 200438, China.
Jiandong DingState Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, 200438, China.
Lin YuState Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, 200438, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Embolization that deliberately blocks target blood vessels through the delivery of embolic agents has emerged as a preferred therapy for various vascular-related diseases. Although various embolic materials are available in clinical practice, including solid and liquid embolic agents, their effectiveness remains limited in target vessels with broad size ranges and complex architectures. These limitations pose challenges in achieving controlled and durable embolization at target sites. To address these issues, we develop an advanced physically/chemically dual-crosslinked hydrogel (DC-gel) composed of thermosensitive poly(ethylene glycol)-poly(

Indexed as

Dual crosslinking strategyEmbolic agentInjectable hydrogelpoly(D-amino acid) componentTransvascular embolization

Identifiers

PMID40688022
PMCPMC12274945

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.